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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
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TTR / Transthyretin

transthyretin

TTR / Transthyretin is transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Gene Name: transthyretin
Synonyms: TTR, ATTR, CTS1, CTS, HsT2651, PALB, Prealbumin, TBPA, Transthyretin, Carpal tunnel syndrome 1, Prealbumin, amyloidosis type I, Thyroxine-binding prealbumin
Target Sequences: NM_000371 NP_000362.1 P02766

Publications (2)

1
Gene expression and functional annotation of human choroid plexus epithelium failure in Alzheimer's disease. Bergen AA, Kaing S, ten Brink JB; Netherlands Brain Bank, Gorgels TG, Janssen SF. BMC genomics. 2015 16:956. (IHC; Human) [Full Text Article] [PubMed:26573292] [PMC:PMC4647590] Related Antibodies: LS-B2864.
2
A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing. Finn JD, Smith AR, Patel MC, Shaw L, Youniss MR, van Heteren J, Dirstine T, Ciullo C, Lescarbeau R, Seitzer J, Shah RR, Shah A, Ling D, Growe J, Pink M, Rohde E, Wood KM, Salomon WE, Harrington WF, Dombrowski C, Strapps WR, Chang Y, Morrissey DV. Cell reports. 2018 February;22:2227-2235. [Full Text Article] [PubMed:29490262] Related Antibodies: LS-C407961.

Viewing 1-25 of 197 items
TTR / Transthyretin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Mouse Monoclonal [clone 10E1] (IgG2a,k) to Human TTR / Transthyretin
Human
ELISA, IHC-P, IP, WB
Unconjugated
50µl   1mg/ml   $425.00
TTR / Transthyretin Antibody - Anti-TTR / Transthyretin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Cancer Pathology
Cancer
Goat Polyclonal to Human TTR / Transthyretin
Mouse, Human
ELISA, IHC-P
Unconjugated
250µg   1mg/ml   $425.00
TTR / Transthyretin Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Fast Shipping
Rabbit Polyclonal to Human TTR / Transthyretin
IHC-P, SWB
Unconjugated
50µg   50µl   1mg/ml   $425.00
TTR / Transthyretin Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
Fast Shipping
Rabbit Polyclonal to Human TTR / Transthyretin
IHC-P, SWB
Unconjugated
50µg   0.88mg/ml   $425.00
TTR / Transthyretin Antibody - Anti-TTR / Transthyretin antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Mouse Monoclonal [clone 9G6] (IgG1,k) to Human TTR / Transthyretin
Human
IHC, IHC-P, IP, WB
Unconjugated
50µl   1mg/ml   $425.00
TTR / Transthyretin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Goat Polyclonal to Human TTR / Transthyretin
Human
ELISA, Flo, ID, IHC, IHC-P, IP, WB
Unconjugated
0.5mg   1mg/ml   $425.00
TTR / Transthyretin Antibody - Anti-TTR / Transthyretin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Rabbit Polyclonal (IgG) to Human TTR / Transthyretin
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50µl   $425.00
TTR / Transthyretin Antibody - Anti-TTR / Transthyretin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Goat Polyclonal to Human TTR / Transthyretin
Human, Monkey
ELISA, IHC, IHC-P, Peptide-ELISA
Unconjugated
50µg   0.5mg/ml   $425.00
TTR / Transthyretin Antibody - Anti-TTR / Transthyretin antibody IHC of human pancreas, islets of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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Chicken Polyclonal (IgY) to Human TTR / Transthyretin
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
TTR / Transthyretin Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal to Human TTR / Transthyretin
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
TTR / Transthyretin Antibody - Anti-TTR / Transthyretin antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Goat Polyclonal (IgG) to Human TTR / Transthyretin
Human
ELISA, IHC, IHC-P
Unconjugated
0.25mg   1mg/ml   $425.00
TTR / Transthyretin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human TTR / Transthyretin
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
TTR / Transthyretin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Pig Polyclonal to Human TTR / Transthyretin
Human
ID, IHC-P
Unconjugated
0.05ml   $425.00
TTR / Transthyretin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Goat Polyclonal to Human TTR / Transthyretin
Human
ELISA, ID, IE, IHC-P
Unconjugated
0.05ml   $425.00
TTR / Transthyretin Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human TTR / Transthyretin
Rat
IHC, IHC-P
Unconjugated
50µl   $425.00
TTR / Transthyretin Antibody - Prealbumin antibody IHC-paraffin. IHC(P): Mouse Pancreas Tissue.
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Rabbit Polyclonal to Rat TTR / Transthyretin
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
100µg   $355.00
Select
Mouse Monoclonal (IgG1,k) to Human TTR / Transthyretin
Human
ELISA, WB
Unconjugated
50µl   $425.00
Select
Goat Polyclonal (IgG) to Human TTR / Transthyretin
Human
ELISA
Unconjugated
1ml   $415.00
Select
Rabbit Polyclonal (IgG) to Monkey-Cynomolgus TTR / Transthyretin
Monkey-Cynomolgus
ELISA
Biotin Conjugated
50µg   $285.00; 100µg   0.25mg/ml   $385.00
TTR / Transthyretin Antibody - Prealbumin antibody IHC-paraffin. IHC(P): Mouse Pancreas Tissue.
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Rabbit Polyclonal to Mouse TTR / Transthyretin
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
100µg   $355.00
TTR / Transthyretin Antibody - Western Blot analysis of TTR expression in transfected 293T cell line by TTR monoclonal antibody (M01), clone 4D8.Lane 1: TTR transfected lysate(15.9 KDa).Lane 2: Non-transfected lysate.
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Mouse Monoclonal [clone 4D8] (IgG1,k) to Human TTR / Transthyretin
Human
ELISA, WB
Unconjugated
100µg   $365.00
TTR / Transthyretin Antibody - TTR Antibody (RB19657) IHC of formalin-fixed and paraffin-embedded human hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human TTR / Transthyretin
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
TTR / Transthyretin Antibody - Western blot of recombinant TTR / Transthyretin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Mouse TTR / Transthyretin
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $285.00; 500µl   0.5mg/ml   $415.00; 1ml   0.5mg/ml   $485.00
TTR / Transthyretin Antibody - Western blot of recombinant TTR / Transthyretin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Mouse TTR / Transthyretin
Mouse
WB
Biotin Conjugated
200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $445.00; 1ml   0.5mg/ml   $530.00
Select
Guinea pig Polyclonal (IgG) to Human TTR / Transthyretin
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   0.42mg/ml   $385.00

Viewing 1-25 of 197 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).