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BACE1 / BACE
beta-site APP-cleaving enzyme 1
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| Gene Name: | beta-site APP-cleaving enzyme 1 |
| Family/Subfamily: | Protease , Aspartic A1 |
| Synonyms: | BACE1, APP beta-secretase, Asp 2, ASP2, Aspartyl protease 2, Aspartylprotease 2, Beta-secretase, Beta-site APP-cleaving enzyme, BACE, HSPC104, KIAA1149, B-Secretase, Beta-secretase 1, Memapsin-2 |
| Target Sequences: | NM_012104 NP_036236.1 P56817 |
Publications (1)
1
Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. Kuzuya A, Zoltowska KM, Post KL, Arimon M, Li X, Svirsky S, Maesako M, Muzikansky A, Gautam V, Kovacs D, Hyman BT, Berezovska O. BMC biology. 2016 14:25. (WB; Human)
[Full Text Article]
[PubMed:27036734]
[PMC:PMC4818459]
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Neuroscience
Fast Shipping
BACE1 / BACE Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
BACE1 / BACE Mouse anti-Human Monoclonal Antibody
Mouse, Human
ELISA, IP, Neut, WB
Unconjugated
100 µg/$941
Fast Shipping
BACE1 / BACE Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
BACE1 / BACE Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$930
BACE1 / BACE Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
BACE1 / BACE Rabbit anti-Human Polyclonal (aa452-501) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Neuroscience
BACE1 / BACE Rabbit anti-Human Polyclonal (aa72-121) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
BACE1 / BACE Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$860
BACE1 / BACE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
BACE1 / BACE Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, IF, IHC, WB
Unconjugated
0.1 mg/$460
BACE1 / BACE Rabbit anti-Human Monoclonal Antibody
Mouse, Rat, Human
IP, WB
Unconjugated
20 µl/$469; 100 µl/$702
BACE1 / BACE Rabbit anti-Mouse Polyclonal (aa251-300) Antibody
Mouse
WB
Unconjugated
100 µl/$424
BACE1 / BACE Rabbit anti-Human Polyclonal (aa170-428) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
BACE1 / BACE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
50 µg/$294; 100 µg/$360
BACE1 / BACE Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
BACE1 / BACE Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IF
Unconjugated
100 µl/$412
BACE1 / BACE Rabbit anti-Human Polyclonal (440-520 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
BACE1 / BACE Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
BACE1 / BACE Rabbit anti-Human Polyclonal (Asp492) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
BACE1 / BACE Rabbit anti-Human Polyclonal (pSer498) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
BACE1 / BACE Rabbit anti-Human Polyclonal (pSer498) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
BACE1 / BACE Rabbit anti-Human Polyclonal (pSer498) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
BACE1 / BACE Rabbit anti-Human Polyclonal (pSer498) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
BACE1 / BACE Mouse anti-Human Monoclonal (3C1C3) Antibody
Human
ELISA, Flo
Unconjugated
100 µl/$459
BACE1 / BACE Rabbit anti-Human Polyclonal (aa38-70) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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product results
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