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SENP3

SUMO1/sentrin/SMT3 specific peptidase 3

Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Gene Name: SUMO1/sentrin/SMT3 specific peptidase 3
Family/Subfamily: Protease , Cysteine C48
Synonyms: SENP3, DKFZP586K0919, Sentrin-specific protease 3, SSP3, SUSP3, Smt3-specific isopeptidase 1, SMT3IP1, SUMO-1-specific protease 3
Target Sequences: NM_015670 NP_056485.2 Q9H4L4

☰ Filters
Antibodies (21)
Proteins (3)
Over-Expression Lysate (2)
Primary (21)
Recombinant (1)
SENP3 (24)
Human (21)
Mouse (10)
Rat (5)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Hamster (4)
Horse (4)
Monkey (5)
Rabbit (4)
IHC (15)
IHC-P (5)
WB (20)
ELISA (11)
IP (3)
Peptide-ELISA (1)
rabbit (21)
Product Group
IHCPlus (1)
IgG (14)
polyclonal pc (21)
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (12)
aa1-30 (8)
aa36-85 (4)
10-90 aa, N-terminal (1)
N-Terminus (1)
Tyr24 (1)
aa1-50 (1)
aa10-59 (1)
aa275-325 (1)
No (24)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
SENP3 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
SENP3 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$525
SENP3 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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SENP3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$376
Select
SENP3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$614
Select
SENP3 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$767
Select
SENP3 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$767
Select
SENP3 Rabbit anti-Human Polyclonal (aa1-30) (AP) Antibody
Human
ELISA, IHC, WB
AP Conjugated
200 µl/$767
Select
SENP3 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$767
Select
SENP3 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$767
Select
SENP3 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$767
Select
SENP3 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µl/$277; 100 µl/$308; 200 µl/$374
SENP3 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP3 antibody.
Select
SENP3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$347
Select
SENP3 Rabbit anti-Human Polyclonal (aa275-325) Antibody
Human
IHC, IP, WB
Unconjugated
100 µl/$457
SENP3 Antibody - Immunohistochemical analysis of SENP3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
SENP3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$289
SENP3 Antibody - IHC of SENP3 (Y24) pAb in paraffin-embedded human breast carcinoma tissue.
Select
SENP3 Rabbit anti-Human Polyclonal (Tyr24) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$319; 100 µl/$393
SENP3 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP3 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
SENP3 Rabbit anti-Human Polyclonal (aa10-59) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$306; 100 µl/$366
Select
SENP3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$396
SENP3 Antibody - Western blot analysis SENP3 using HuvEc whole cells lysates
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SENP3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$369; 200 µl/$411
SENP3 Antibody - SENP3 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SENP3 Rabbit anti-Human Polyclonal (aa36-85) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
WB
Unconjugated
100 µl/$434
SENP3 Antibody - SENP3 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SENP3 Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$459
SENP3 Antibody - SENP3 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SENP3 Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$459
SENP3 Antibody - SENP3 antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SENP3 Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$459
SENP3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
2 µg/$421
SENP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
64.8 kDa
20 µg/$130
SENP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
64.8 kDa
100 µg/$458
Viewing 1-24 of 24 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).