Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

SST / Somatostatin

somatostatin

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.

Gene Name: somatostatin
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: SST, Somatostatin-28, SMST, Somatostatin-14, Somatostatin
Target Sequences: NM_001048 NP_001039.1 P61278

Publications (6)

1
Characterization of Autonomic Nerve Markers and Lymphocyte Subsets in the Ileal Peyer’s Patch of Pigs Infected Experimentally with Brachyspira hyodysenteriae. J. Kaleczyc, P. Podlasz, A. Winnick, W. Wasowicz, W. Sienkiewicz, J. Zmudzki and M. Lakomy. Journal of comparative pathology. 2010 143:248-57. (IHC-Fr; Pig) [Full Text Article] [PubMed:20605161]
2
A smad signaling network regulates islet cell proliferation. El-Gohary Y, Tulachan S, Wiersch J, Guo P, Welsh C, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G. Diabetes. 2014 63:224-36. (IHC-P; Human) [Full Text Article] [PubMed:24089514] [PMC:PMC3868054]
3
Establishment of a diabetes mellitus type 1 model in the common marmoset. Yuan W, Fukuda S, Inoue T, Okochi H, Sasaki E, Shimoda M. Science advances. 2019 October;9:14546. [Full Text Article] [PubMed:31601983] [PMC:PMC6787219]
4
Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain state. T Fuchs, S J Jefferson, A Hooper, P-Hp Yee, J Maguire, B Luscher. Molecular psychiatry. 2017 June;22:920-930. [Full Text Article] [PubMed:27821870] [PMC:PMC5422144]
5
Itch-associated Neuropeptides and Their Receptor Expression in Dog Dorsal Root Ganglia and Spinal Cord. Joshua J Wheeler, B Duncan Lascelles, Thierry Olivry, Santosh K Mishra. Acta dermato-venereologica. 2019 Nov;99:1131-1135. [Full Text Article] [PubMed:31449313]
6
Multifaceted secretion of htNSC-derived hypothalamic islets induces survival and antidiabetic effect via peripheral implantation in mice. Yizhe Tang , Juan Pablo Zuniga-Hertz , Cheng Han, Bin Yu, Dongsheng Cai. eLife. 2020 Feb;9:e52580. [Full Text Article] [PubMed:32081132] [PMC:PMC7062468]
more

Your search did not match any products.


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).