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AKR1B10

aldo-keto reductase family 1, member B10 (aldose reductase)

Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.

Gene Name: aldo-keto reductase family 1, member B10 (aldose reductase)
Synonyms: AKR1B10, AKR1B11, Aldose reductase-like peptide, ALDRLn, AKR1B12, Aldose reductase-like, Aldose reductase-like 1, ARP, HARP, HSI, Small intestine reductase, ARL-1, SI reductase
Target Sequences: NM_020299 NP_064695.3 O60218

Publications (6)

1
Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention. Yan R, Zu X, Ma J, Liu Z, Adeyanju M, Cao D. International journal of cancer. Journal international du cancer. 2007 121:2301-6. [PubMed:17597105]
2
Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cells. Ma J, Yan R, Zu X, Cheng JM, Rao K, Liao DF, Cao D. The Journal of biological chemistry. 2008 283:3418-23. [PubMed:18056116]
3
Oxidation of PAH trans-dihydrodiols by human aldo-keto reductase AKR1B10. Quinn AM, Harvey RG, Penning TM. Chemical research in toxicology. 2008 21:2207-15. [PubMed:18788756] [PMC:PMC2645959]
4
Aldo-keto reductase family 1 member B10 promotes cell survival by regulating lipid synthesis and eliminating carbonyls. Wang C, Yan R, Luo D, Watabe K, Liao DF, Cao D. The Journal of biological chemistry. 2009 284:26742-8. [PubMed:19643728] [PMC:PMC2785362]
5
Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosis. Starmann J, Flth M, Spindelbck W, Lanz KL, Lackner C, Zatloukal K, Trauner M, Sltmann H. PloS one. 2012 7:e46584. (IHC; Human) [PubMed:23071592] [PMC:PMC3468618]
6
Aldoketoreductase family 1B10 (AKR1B10) as a biomarker to distinguish hepatocellular carcinoma from benign liver lesions. Matkowskyj KA, Bai H, Liao J, Zhang W, Li H, Rao S, Omary R, Yang GY. Human pathology. 2014 45:834-43. (ICC; Human) [Full Text Article] [PubMed:24656094] [PMC:PMC4030546]
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☰ Filters
Antibodies (31)
cDNAs (28)
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Competitive EIA (2)
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AKR1B10 (71)
Human (35)
Mouse (10)
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Chimpanzee (3)
Gibbon (3)
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rabbit (29)
mouse (1)
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monoclonal mc (1)
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AKR1B10 Antibody - Anti-AKR1B10 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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AKR1B10 Mouse anti-Human Monoclonal (1A6) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$495
AKR1B10 Antibody - Anti-AKR1B10 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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AKR1B10 Rabbit anti-Human Polyclonal (aa100-200) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
AKR1B10 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$654
AKR1B10 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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AKR1B10 Rabbit anti-Human Polyclonal (aa1-316) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AKR1B10 Antibody - Western blot blot of extracts of various cell lines, using AKR1B10 antibody.
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AKR1B10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
AKR1B10 Antibody - Immunohistochemistry of paraffin-embedded human small intestine using antibody at 1:100 dilution.
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AKR1B10 Rabbit anti-Human Polyclonal (aa1-316) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$251; 100 µl/$285
AKR1B10 Antibody - Immunohistochemistry - Anti-AKR1B10 Picoband Antibody
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AKR1B10 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$397
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AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$614
Select
AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$767
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AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$767
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AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$767
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AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (AP) Antibody
Human
ELISA, WB
AP Conjugated
200 µl/$767
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AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$767
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AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$767
AKR1B10 Antibody - IHC testing of FFPE human intestinal cancer tissue with AKR1B10 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
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AKR1B10 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, WB
Unconjugated
100 µg/$480
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AKR1B10 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$369; 200 µl/$411
AKR1B10 Antibody - Antibody (0.03 ug/ml) staining of A549 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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AKR1B10 Goat anti-Human Polyclonal (aa303-315) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$451
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AKR1B10 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$622
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AKR1B10 Rabbit anti-Human Polyclonal (AP) Antibody
Human
WB
AP Conjugated
100 µl/$774
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AKR1B10 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$774
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AKR1B10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$278; 120 µl/$338; 200 µl/$440
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AKR1B10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$439
AKR1B10 Antibody - AKR1B10 antibody ARP42553_T100-NP_064695-AKR1B10(aldo-keto reductase family 1, member B10 (aldose reductase)) Antibody Western blot of A549 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AKR1B10 Rabbit anti-Human Polyclonal (aa51-100) Antibody
Zebrafish, Horse, Mouse, Human
WB
Unconjugated
100 µl/$355
AKR1B10 Antibody - AKR1B10 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The AKR1B10 antibody detected the AKR1B10 protein (arrow).
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AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) Antibody
Human
WB
Unconjugated
400 µl/$376
AKR1B10 Antibody - Western blot analysis of AKR1B10 expression in HEK293T (A); mouse liver (B); mouse kidney (C) whole cell lysates.
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AKR1B10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$276; 100 µl/$311; 200 µl/$376
Viewing 1-25 of 71 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).