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ANPEP / CD13

alanyl (membrane) aminopeptidase

ANPEP (CD13) is a broad specificity aminopeptidase involved in the metabolism of biologically active peptides, phagocytosis, and myeloid cell differentiation. It is known to have bactericidal and tumoricidal activity. ANPEP plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. It is thought to be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. ANPEP cleaves antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. It is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. In normal tissue, ANPEP is present on a majority of cells of myeloid origin, including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also found on fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. In cancer and disease, it is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. It is expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemia. It is absent in normal lymphocytes, platelets and erythrocytes. In the case of human coronavirus 229E (HCoV-229E) infection, it serves as receptor for HCoV-229E spike glycoprotein. It also mediates human cytomegalovirus (HCMV) infection. Additionally, it may play a critical role in the pathogenesis of cholesterol gallstone disease.

Gene Name: alanyl (membrane) aminopeptidase
Family/Subfamily: Exopeptidase , Metallopeptidase M1
Synonyms: ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1
Target Sequences: NM_001150 NP_001141.2 P15144

☰ Filters
Antibodies (175)
ELISA Kits (20)
Proteins (12)
Assay Kits (1)
Custom (4)
Enzymatic Activity Assay (1)
Primary (175)
Recombinant (12)
Sandwich (16)
ANPEP / CD13 (208)
Human (148)
Mouse (37)
Rat (25)
Bovine (6)
Chicken (1)
Dog (1)
Guinea pig (4)
Horse (7)
Monkey (1)
Non-Human Primate (5)
Non-Human Primates (8)
Pig (1)
IHC (53)
IHC-Fr (29)
IHC-P (29)
WB (81)
Flo (74)
ELISA (35)
Func (11)
ICC (2)
IF (12)
IHC-Fx (1)
IP (20)
Peptide-ELISA (3)
rabbit (64)
mouse (96)
goat (2)
rat (12)
sheep (1)
Product Group
Antibodies to Coronavirus-Associated Targets (175)
Coronavirus Antibodies Proteins cDNAs (187)
Coronavirus Detection (20)
ELISA Kits for Associated Targets (20)
IHCPlus (1)
PathPlus Cancer (1)
PathPlus Cancer Pathology (1)
SARS-CoV-2 Associated Proteins (12)
IgG (28)
IgG1 (53)
IgG1,k (11)
IgG2a (30)
IgG2a,k (9)
IgG2b (2)
monoclonal mc (109)
polyclonal pc (66)
011 (1)
11 (1)
123H1 (2)
1C7D7 (1)
1G1 (1)
22A5 (9)
2F10 (2)
38C12 (3)
422 (1)
496CT9.1.1 (3)
505CT12.1.2 (4)
APN/514 (2)
B347 (1)
BF10 (2)
B-F10 (2)
CC81 (1)
CVS19 (3)
E735 (3)
ER-BMDM1 (4)
OTI2E4 (2)
OTI3F8 (2)
R3-63 (4)
TUK 1 (3)
Tük 1 (3)
UMAB275 (2)
WM15 (21)
WM-15 (WM15) (1)
96-Well Microplate (4)
96-Well Strip Plate (16)
AF488 Conjugated (1)
AP Conjugated (4)
APC (3)
APC Conjugated (9)
Azide-free (6)
Biotin Conjugated (12)
BSA-free (3)
Carrier-free (4)
Concentrated (4)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
DY594 Conjugated (1)
FITC Conjugated (22)
HRP Conjugated (9)
Low Endotoxin (3)
PE (1)
PE Conjugated (15)
PerCP Conjugated (1)
Preservative Free (6)
Ready-to-Use (1)
RPE Conjugated (5)
TC Conjugated (1)
Unconjugated (89)
aa156-184 (8)
aa290-533 (8)
aa668-967 (8)
aa720-961 (8)
aa142-191 (4)
C-Terminus (2)
881-930 aa, C-terminal (1)
C-terminal (1)
Internal region (near C-Terminus) (1)
Internal region (near N-Terminus) (1)
aa506-688 (1)
aa615-641 (1)
aa69-967 (1)
aa868-917 (1)
No (208)
Spectrophotometry (fluorometric) (1)
Microplate fluorometer (1)
Cell Culture Supernatants (5)
Plasma (16)
Serum (16)
Tissue Homogenates (7)
10His, N-terminus + Myc, C-terminus (1)
6His, C-terminus (2)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
His,C-terminus (1)
His-T7 (3)
Myc-DDK (Flag) (1)
Human (6)
Mouse (3)
Pig (1)
Rat (2)
E. coli (5)
HEK 293 Cells (2)
Human Cells (3)
Wheat Germ Extract (2)
Purified (5)
Low endotoxin level (4)
ANPEP / CD13 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
ANPEP / CD13 Mouse anti-Human Monoclonal (aa668-967) (2F10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ANPEP / CD13 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (38C12) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.05 ml/$460
ANPEP / CD13 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
312 - 20000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (B347) Antibody
Human
Flo, IF, IHC
Unconjugated
200 µg/$314
Select
ANPEP / CD13 Rat anti-Mouse Monoclonal (FITC) (R3-63) Antibody
Mouse
Flo, IHC, IHC-Fr
FITC Conjugated
25 µg/$266; 50 µg/$310; 0.1 mg/$406
Select
ANPEP / CD13 Sheep anti-Human Polyclonal (aa69-967) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$762
ANPEP / CD13 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Select
ANPEP / CD13 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$284; 100 µg/$351
ANPEP / CD13 Antibody - Western blot of recombinant ANPEP / CD13.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ANPEP / CD13 Rabbit anti-Rat Polyclonal (aa290-533) Antibody
Rat, Human
WB
Unconjugated
100 µl/$302; 200 µl/$345; 500 µl/$489; 1 ml/$561
ANPEP / CD13 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$746
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (22A5) Antibody
Human
Flo, IHC, IHC-P
Unconjugated
100 µg/$351
ANPEP / CD13 Antibody - Human peripheral blood granulocytes stained with purified WM15, followed by anti-mouse IgGs FITC
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ANPEP / CD13 Mouse anti-Human Monoclonal (WM15) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
25 µg/$230; 100 µg/$256
Select
ANPEP / CD13 Rabbit anti-Human Monoclonal (Preservative Free) (011) Antibody
Human
ICC, IF
Unconjugated, Preservative Free
50 µl/$290; 100 µl/$350
Select
ANPEP / CD13 Rat anti-Mouse Monoclonal (ER-BMDM1) Antibody
Mouse
IHC, IHC-P
Unconjugated
100 µg/$533
ANPEP / CD13 Antibody - Western blot of recombinant ANPEP / CD13.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ANPEP / CD13 Rabbit anti-Mouse Polyclonal (aa720-961) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$297; 200 µl/$338; 500 µl/$475; 1 ml/$543
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (E735) Antibody
Human
Flo
Unconjugated
100 µg/$325
Select
ANPEP / CD13 Rat anti-Mouse Monoclonal (PE) Antibody
Mouse
Flo
PE Conjugated
100 Tests/$677
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (B-F10) Antibody
Human
Flo, IF, IHC, IHC-Fr
Unconjugated
20 µg/$347; 100 µg/$522
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (B-F10) Antibody
Human
Flo, IF, IHC, IHC-Fr
Unconjugated, Azide-free, BSA-free
100 µg/$522
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (APN/514) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$347; 100 µg/$522
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (APN/514) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$522
ANPEP / CD13 Antibody - IHC testing of FFPE human brain with CD13 antibody (clone WM15).
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (WM15) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$347; 100 µg/$522
ANPEP / CD13 Antibody - IHC testing of FFPE human brain with CD13 antibody (clone WM15). This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (WM15) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$522
Select
ANPEP / CD13 Mouse anti-Horse Monoclonal (RPE) (CVS19) Antibody
Horse
Flo
RPE Conjugated
100 Tests/$537
ANPEP / CD13 Antibody - Immunochemical staining of human ANPEP in human kidney with rabbit polyclonal antibody at 1:10000 dilution, formalin-fixed paraffin embedded sections.
Select
ANPEP / CD13 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, IHC-P
Unconjugated, Preservative Free
50 µl/$275; 100 µl/$312; 200 µl/$350
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (WM15) Antibody
Human
ELISA, Flo, IHC, IP
Unconjugated
100 µg/$653
Viewing 1-25 of 208 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).