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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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ANPEP / CD13

alanyl (membrane) aminopeptidase

ANPEP (CD13) is a broad specificity aminopeptidase involved in the metabolism of biologically active peptides, phagocytosis, and myeloid cell differentiation. It is known to have bactericidal and tumoricidal activity. ANPEP plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. It is thought to be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. ANPEP cleaves antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. It is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. In normal tissue, ANPEP is present on a majority of cells of myeloid origin, including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also found on fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. In cancer and disease, it is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. It is expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemia. It is absent in normal lymphocytes, platelets and erythrocytes. In the case of human coronavirus 229E (HCoV-229E) infection, it serves as receptor for HCoV-229E spike glycoprotein. It also mediates human cytomegalovirus (HCMV) infection. Additionally, it may play a critical role in the pathogenesis of cholesterol gallstone disease.

Gene Name: alanyl (membrane) aminopeptidase
Family/Subfamily: Exopeptidase , Metallopeptidase M1
Synonyms: ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1
Target Sequences: NM_001150 NP_001141.2 P15144

☰ Filters
Antibodies (177)
ELISA Kits (21)
Proteins (14)
Assay Kits (1)
Custom (4)
Enzymatic Activity Assay (1)
Primary (177)
Recombinant (12)
Sandwich (17)
ANPEP / CD13 (213)
Human (150)
Mouse (37)
Rat (26)
Bovine (6)
Chicken (1)
Dog (1)
Guinea pig (4)
Horse (7)
Monkey (1)
Non-Human Primate (5)
Non-Human Primates (8)
Pig (1)
IHC (55)
IHC-Fr (31)
IHC-P (29)
WB (81)
Flo (76)
ELISA (36)
Func (11)
ICC (2)
IF (12)
IHC-Fx (1)
IP (21)
Peptide-ELISA (3)
rabbit (64)
mouse (98)
goat (2)
rat (12)
sheep (1)
Product Group
Antibodies to Coronavirus-Associated Targets (177)
Coronavirus Detection (198)
Coronavirus Proteomics (14)
ELISA Kits for Associated Targets (21)
IHCPlus (1)
PathPlus Cancer (1)
PathPlus Cancer Pathology (1)
SARS-CoV-2 Associated Proteins (14)
IgG (29)
IgG1 (54)
IgG1,k (11)
IgG2a (30)
IgG2a,k (9)
IgG2b (2)
monoclonal mc (111)
polyclonal pc (66)
011 (1)
11 (1)
123H1 (2)
1C7D7 (1)
1G1 (1)
22A5 (9)
2F10 (2)
38C12 (3)
422 (1)
496CT9.1.1 (3)
505CT12.1.2 (4)
APN/514 (2)
B347 (1)
BF10 (2)
B-F10 (2)
CC81 (1)
CVS19 (3)
E735 (3)
ER-BMDM1 (4)
OTI2E4 (2)
OTI3F8 (2)
R3-63 (4)
TUK 1 (3)
Tük 1 (3)
UMAB275 (2)
WM15 (22)
WM-15 (WM15) (1)
96-Well Microplate (4)
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AF488 Conjugated (1)
AP Conjugated (4)
APC (3)
APC Conjugated (9)
Azide-free (6)
Biotin Conjugated (13)
Carrier-free (4)
Concentrated (4)
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DY594 Conjugated (1)
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HRP Conjugated (9)
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RPE Conjugated (5)
TC Conjugated (1)
Unconjugated (90)
aa156-184 (8)
aa290-533 (8)
aa668-967 (8)
aa720-961 (8)
aa142-191 (4)
C-Terminus (2)
881-930 aa, C-terminal (1)
C-terminal (1)
Internal region (near C-Terminus) (1)
Internal region (near N-Terminus) (1)
aa506-688 (1)
aa615-641 (1)
aa69-967 (1)
aa868-917 (1)
No (213)
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Microplate fluorometer (1)
Cell Culture Supernatants (5)
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10His, N-terminus + Myc, C-terminus (1)
6His, C-terminus (2)
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GST (1)
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Human (8)
Mouse (3)
Pig (1)
Rat (2)
E. coli (5)
HEK 293 Cells (2)
Human Cells (3)
Wheat Germ Extract (2)
Purified (7)
Low endotoxin level (4)
ANPEP / CD13 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
ANPEP / CD13 Mouse anti-Human Monoclonal (aa668-967) (2F10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$425
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (B347) Antibody
Human
Flo, IF, IHC
Unconjugated
200 µg/$275
Select
ANPEP / CD13 Rat anti-Mouse Monoclonal (FITC) (R3-63) Antibody
Mouse
Flo, IHC, IHC-Fr
FITC Conjugated
0.1 mg/$365
Select
ANPEP / CD13 Sheep anti-Human Polyclonal (aa69-967) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$740
ANPEP / CD13 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (38C12) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$425
ANPEP / CD13 Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Select
ANPEP / CD13 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$245; 100 µg/$385
ANPEP / CD13 Antibody - Western blot of recombinant ANPEP / CD13.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ANPEP / CD13 Rabbit anti-Rat Polyclonal (aa290-533) Antibody
Rat, Human
WB
Unconjugated
100 µl/$265; 200 µl/$305; 500 µl/$445; 1 ml/$545
ANPEP / CD13 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$700
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (22A5) Antibody
Human
Flo, IHC, IHC-P
Unconjugated
100 µg/$315
ANPEP / CD13 Antibody - Human peripheral blood granulocytes stained with purified WM15, followed by anti-mouse IgGs FITC
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (WM15) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
25 µg/$185; 100 µg/$215
Select
ANPEP / CD13 Rabbit anti-Human Monoclonal (Preservative Free) (011) Antibody
Human
ICC, IF
Unconjugated, Preservative Free
50 µl/$245; 100 µl/$305
Select
ANPEP / CD13 Rat anti-Mouse Monoclonal (ER-BMDM1) Antibody
Mouse
IHC, IHC-P
Unconjugated
100 µg/$515
ANPEP / CD13 Antibody - Western blot of recombinant ANPEP / CD13.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ANPEP / CD13 Rabbit anti-Mouse Polyclonal (aa720-961) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$255; 200 µl/$295; 500 µl/$435; 1 ml/$515
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (E735) Antibody
Human
Flo
Unconjugated
100 µg/$285
Select
ANPEP / CD13 Rat anti-Mouse Monoclonal (PE) Antibody
Mouse
Flo
PE Conjugated
100 Tests/$650
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (B-F10) Antibody
Human
Flo, IF, IHC, IHC-Fr
Unconjugated
20 µg/$295; 100 µg/$465
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (Azide-free) (B-F10) Antibody
Human
Flo, IF, IHC, IHC-Fr
Unconjugated, Azide-free
100 µg/$465
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (APN/514) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$295; 100 µg/$465
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (Azide-free) (APN/514) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free
100 µg/$465
ANPEP / CD13 Antibody - IHC testing of FFPE human brain with CD13 antibody (clone WM15).
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (WM15) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$295; 100 µg/$465
ANPEP / CD13 Antibody - IHC testing of FFPE human brain with CD13 antibody (clone WM15). This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (Azide-free) (WM15) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free
100 µg/$465
ANPEP / CD13 Antibody - Immunochemical staining of human ANPEP in human kidney with rabbit polyclonal antibody at 1:10000 dilution, formalin-fixed paraffin embedded sections.
Select
ANPEP / CD13 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, ICC, IF, IHC-P
Unconjugated, Preservative Free
50 µl/$235; 100 µl/$275; 200 µl/$305
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (WM15) Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
2 ml/$1,245
Select
ANPEP / CD13 Mouse anti-Human Monoclonal (WM15) Antibody
Human
ELISA, Flo, IHC, IP
Unconjugated
100 µg/$620
Select
ANPEP / CD13 Mouse anti-Human Monoclonal Antibody
Human, Monkey
ELISA, Flo, Func, IHC, IHC-Fr, IHC-P, IP
Unconjugated
500 µg/$875
Viewing 1-25 of 213 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).