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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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ACTN1

actinin, alpha 1

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: actinin, alpha 1
Synonyms: ACTN1, Alpha-actinin-1, Actinin 1 smooth muscle, Actinin, alpha 1, F-actin cross-linking protein, Non-muscle alpha-actinin-1, ASMA
Target Sequences: NM_001102 NP_001093.1 P12814

☰ Filters
Antibodies (65)
ELISA Kits (9)
Proteins (6)
Custom (4)
Over-Expression Lysate (2)
Primary (65)
Recombinant (4)
Sandwich (5)
ACTN1 (80)
Human (66)
Mouse (36)
Rat (27)
Bat (1)
Bovine (10)
Chicken (7)
Chimpanzee (6)
Dog (8)
Gibbon (6)
Guinea pig (9)
Hamster (5)
Horse (5)
Monkey (13)
Pig (5)
Rabbit (16)
Sheep (1)
Zebrafish (8)
IHC (30)
IHC-Fr (3)
IHC-P (6)
WB (63)
Flo (8)
ELISA (15)
ICC (9)
IF (8)
IP (4)
Peptide-ELISA (1)
rabbit (47)
mouse (17)
goat (1)
Product Group
IHCPlus (1)
IgG (32)
IgG1 (11)
IgG2a (2)
IgG2a,k (1)
IgG3,k (1)
monoclonal mc (17)
polyclonal pc (48)
1D4 (1)
3F1 (1)
AT1D10 (1)
CB11 (1)
OTI7A4 (2)
96-Well Strip Plate (9)
AP Conjugated (3)
APC (1)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (6)
Carrier-free (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (34)
aa1-30 (8)
aa28-260 (8)
N-Terminus (6)
aa671-720 (4)
1-80 aa, N-terminal (1)
40-120 aa, N-terminal (1)
C-Terminus (1)
Tyr193 (1)
aa596-609 (1)
aa650-893 (1)
No (80)
Cell Culture Supernatants (1)
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Plasma (4)
Serum (4)
Tissue Homogenates (2)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
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ACTN1 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$530
Select
ACTN1 Mouse anti-Human Monoclonal (N-Terminus) Antibody
Human
IF, IHC, IP, WB
Unconjugated
100 µl/$620
ACTN1 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
ACTN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µl/$425
Select
ACTN1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Hamster, Human, Monkey
ICC, IF, WB
Unconjugated
100 µl/$530
ACTN1 Antibody - IHC of paraffin-embedded Human breast tissue using anti-ACTN1 mouse monoclonal antibody.
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ACTN1 Mouse anti-Human Monoclonal (OTI7A4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$345
ACTN1 Antibody - IHC of paraffin-embedded Human breast tissue using anti-ACTN1 mouse monoclonal antibody.
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ACTN1 Mouse anti-Human Monoclonal (aa650-893) (Carrier-free) (OTI7A4) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$395
ACTN1 Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ACTN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$325; 200 µl/$375
ACTN1 Antibody - Formalin-fixed and paraffin-embedded human breast carcinoma with ACTN1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ACTN1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$325
ACTN1 Antibody - IHC: Mouse anti-alpha-Actinin (ACTININ (ALPHA), MS X-100UL) staining of MeOH fixed fibroblast.
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ACTN1 Mouse anti-Human Monoclonal Antibody
Human
IF, IHC, IP, WB
Unconjugated
100 µl/$415
ACTN1 Antibody - ICC/IF analysis of ACTN1 in Balb-3T3 cells. The cell was stained with ACTN1 antibody (1:100).The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
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ACTN1 Mouse anti-Human Monoclonal (AT1D10) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$275; 100 µl/$345
Select
ACTN1 Mouse anti-Human Monoclonal Antibody
Rabbit, Mouse, Human
ICC, IHC, IHC-Fr, IP, WB
Unconjugated
200 µg/$710
Select
ACTN1 Mouse anti-Human Monoclonal (HRP) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
HRP Conjugated
100 µl/$905
Select
ACTN1 Mouse anti-Human Monoclonal (Biotin) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
Biotin Conjugated
100 µl/$905
Select
ACTN1 Mouse anti-Human Monoclonal (FITC) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
FITC Conjugated
100 µl/$905
Select
ACTN1 Mouse anti-Human Monoclonal (APC) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
APC Conjugated
100 µl/$905
Select
ACTN1 Mouse anti-Human Monoclonal (PE) Antibody
Rabbit, Mouse, Human
ICC, IHC, WB
PE Conjugated
100 µl/$905
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$740
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$740
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (AP) Antibody
Human
ELISA, Flo, IHC, WB
AP Conjugated
200 µl/$740
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$740
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$740
Select
ACTN1 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$740
Select
ACTN1 Mouse anti-Chicken Monoclonal (CB11) Antibody
Chicken, Human
ELISA, IHC, IHC-Fr, WB
Unconjugated
100 µg/$800
ACTN1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$700
Select
ACTN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$405
Viewing 1-25 of 80 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).