Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ST8SIA4 catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
|Gene Name:||ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4|
|Synonyms:||ST8SIA4, Alpha-2,8-sialyltransferase 8D, PST, Sialyltransferase 8D, SIAT8D, ST8SiaIV, Polysialyltransferase-1, SIAT8-D, Sialytransferase St8Sia IV, ST8SIA-IV|
|Target Sequences:||NM_005668 NP_005659.1 Q92187|
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