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ITGAX / CD11c

integrin, alpha X (complement component 3 receptor 4 subunit)

ITGAX / CD11c is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: integrin, alpha X (complement component 3 receptor 4 subunit)
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGAX, CD11c antigen, Integrin alpha-X, Leu M5, alpha subunit, p150 95 integrin alpha chain, SLEB6, CD11C, Leu M5
Target Sequences: NM_000887 NP_000878.2 P20702

Publications (5)

1
CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. Sadhu C, Ting HJ, Lipsky B, Hensley K, Garcia-Martinez LF, Simon SI, Staunton DE. Journal of leukocyte biology. 2007 81:1395-403. [PubMed:17389580] Related Antibodies: LS-C40809.
2
Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Gurer C, Strowig T, Brilot F, Pack M, Trumpfheller C, Arrey F, Park CG, Steinman RM, Mnz C. Blood. 2008 112:1231-9. [PubMed:18519810] [PMC:PMC2515117] Related Antibodies: LS-C40809.
3
Phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1. Asai A, Okajima F, Nakagawa K, Ibusuki D, Tanimura K, Nakajima Y, Nagao M, Sudo M, Harada T, Miyazawa T, Oikawa S. Journal of lipid research. 2009 50:957-65. [PubMed:19114730] [PMC:PMC2666182] Related Antibodies: LS-C40809.
4
Abundant immunoglobulin E-positive cells in skin lesions support an allergic etiology of atopic dermatitis in the elderly. Tanei R, Hasegawa Y, Sawabe M. Journal of the European Academy of Dermatology and Venereology : JEADV. 2013 27:952-60. (ICC; Human) [Full Text Article] [PubMed:22702954] [PMC:PMC3818699]
5
Dendritic cells in semen of infertile men: association with sperm quality and inflammatory status of the epididymis. Duan YG, Zhang Q, Liu Y, Mou L, Li G, Gui Y, Cai Z. Fertility and sterility. 2014 101:70-77. (ICC; Human) [Full Text Article] [PubMed:24083871]
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☰ Filters
Antibodies (178)
Proteins (6)
Over-Expression Lysate (2)
Primary (178)
Recombinant (4)
ITGAX / CD11c (184)
Human (130)
Mouse (52)
Rat (4)
Bovine (1)
Dog (4)
Monkey (12)
Non-Human Primate (5)
Primate (4)
IHC (73)
IHC-Fr (27)
IHC-P (25)
WB (45)
Flo (109)
Block (2)
ELISA (22)
Func (2)
ICC (1)
IF (21)
IHC-Pfa (1)
IP (30)
rabbit (51)
mouse (89)
chicken (1)
hamster (17)
hamster-armenian (16)
rat (4)
Product Group
IHCPlus (12)
PathPlus Cancer (3)
IgG (50)
IgG,k (5)
IgG1 (55)
IgG1,k (16)
IgG2a (10)
IgG2b (1)
IgG2b,k (4)
IgM (1)
IgY (1)
monoclonal mc (125)
polyclonal pc (51)
recombinant monoclonal rmc (2)
12K26 (1)
223H7 (3)
3.9 (17)
428CT12.2.6.4 (3)
5D11 (1)
6G2D1 (1)
BAQ153A (1)
BU15 (25)
CA11.6A1 (1)
CBR-p150/4G1 (1)
FK24 (1)
HC1/1 (3)
ITGAX/1242 (2)
ITGAX/1243 (3)
ITGAX/1284 (2)
N418 (30)
AF488 Conjugated (3)
AF647 Conjugated (3)
AP Conjugated (7)
APC (2)
APC Conjugated (12)
Azide-free (10)
Biotin Conjugated (18)
BSA-free (4)
Concentrated (1)
Cy3 Conjugated (2)
Cy5 Conjugated (3)
Cy5.5 (3)
Cy5.5 Conjugated (3)
Cy7 Conjugated (5)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (21)
HRP Conjugated (9)
Low Endotoxin (1)
PE (9)
PE Conjugated (18)
PerCP Conjugated (8)
Preservative Free (1)
RPE Conjugated (2)
Supernatant (2)
Unconjugated (61)
Internal (14)
aa1119-1145 (8)
aa143-344 (8)
aa246-274 (8)
aa907-1115 (8)
aa600-850 (4)
CD11c (2)
aa 637-827 (1)
aa1-168 (1)
aa20-1116 (1)
aa287-339 (1)
No (183)
Yes (1)
GST, N-terminus (1)
His-GST (1)
His-T7 (1)
MBP, N-terminus + 6His, C-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
Mouse (2)
293T Cells (1)
Baculovirus (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
ITGAX / CD11c Antibody - Anti-CD11c antibody IHC of Human Colon.  Positive staining neutrophils, negative staining in the septum and vascular endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
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ITGAX / CD11c Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
ITGAX / CD11c Antibody - Anti-CD11c antibody IHC of Human Colon.  Positive staining neutrophils, negative staining in the septum and vascular endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ITGAX / CD11c Rabbit anti-Human Polyclonal (Internal) (Azide-free) (HRP) Antibody
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100 µl/$650
ITGAX / CD11c Antibody - Anti-CD11c antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5-10ug/ml.
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Cancer
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ITGAX / CD11c Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
ITGAX / CD11c Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma with ITGAX Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ITGAX / CD11c Rabbit anti-Human Polyclonal (aa1119-1145) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$381
ITGAX / CD11c Antibody - Western blot of CD11C (8E3) mAb at 1:2000 dilution. Lane 1: MCF-7 whole cell lysate (40 ug). Lane 2: HepG2 whole cell lysate (40 ug).
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ITGAX / CD11c Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$327; 100 µl/$409
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ITGAX / CD11c Hamster anti-Mouse Monoclonal (N418) Antibody
Mouse
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$544; 250 µg/$736
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ITGAX / CD11c Hamster anti-Mouse Monoclonal (Biotin) Antibody
Mouse
Flo, IF, IHC, IP
Biotin Conjugated
100 µl/$719
ITGAX / CD11c Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
ITGAX / CD11c Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$460
ITGAX / CD11c Antibody - Human peripheral blood granulocytes stained with 3.9 PE
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ITGAX / CD11c Mouse anti-Human Monoclonal (3.9) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
25 µg/$233; 100 µg/$262
ITGAX / CD11c Antibody - IHC testing of human tonsil with CD11c antibody (clone ITGAX/1242). Note specific staining of dendritic cells. Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.
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ITGAX / CD11c Mouse anti-Human Monoclonal (aa600-850) (Azide-free, BSA-free) (ITGAX/1242) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$522
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ITGAX / CD11c Hamster-Armenian anti-Mouse Monoclonal (N418) Antibody
Mouse
Flo, IHC, IHC-Pfa, IP
Unconjugated
50 µg/$429; 500 µg/$518
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ITGAX / CD11c Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µg/$498
ITGAX / CD11c Antibody - Western blot of ITGAX / CD11c antibody.
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ITGAX / CD11c Rabbit anti-Mouse Polyclonal (aa907-1115) Antibody
Mouse
WB
Unconjugated
100 µl/$297; 200 µl/$338; 500 µl/$475; 1 ml/$543
ITGAX / CD11c Antibody - Staining of normal human peripheral blood cells with FITC Mouse IgG1, K Isotype Control (open histogram) or FITC anti-human CD11c (filled histogram). Cells in the monocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ITGAX / CD11c Mouse anti-Human Monoclonal (FITC) (3.9) Antibody
Human
Flo
FITC Conjugated
25 Tests/$275; 100 Tests/$342
ITGAX / CD11c Antibody - Immunohistochemistry of paraffin-embedded human lung cancer at dilution 1:100
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ITGAX / CD11c Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$251; 100 µl/$285
ITGAX / CD11c Antibody - Western blot analysis of extracts of various cell lines, using ITGAX antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.
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ITGAX / CD11c Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
ITGAX / CD11c Antibody - CD11c Antibody HC1/1 flow cytometry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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ITGAX / CD11c Mouse anti-Human Monoclonal (HC1/1) Antibody
Human
Block, Flo, Func, IF, IHC, IHC-Fr
Unconjugated
20 µg/$347; 100 µg/$522
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ITGAX / CD11c Hamster-Armenian anti-Mouse Monoclonal (Azide-free, Low Endotoxin) (N418) Antibody
Mouse
Flo, IF, IHC, IP
Unconjugated, Azide-free, Low Endotoxin
50 µg/$261
ITGAX / CD11c Protein - Recombinant  Integrin Alpha X By SDS-PAGE
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E. coli
His-GST
53.9 kDa
10 µg/$267; 50 µg/$393; 100 µg/$627; 200 µg/$784; 1 mg/$1,781
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ITGAX / CD11c Mouse anti-Human Monoclonal (6G2D1) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$415
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ITGAX / CD11c Hamster-Armenian anti-Mouse Monoclonal (N418) Antibody
Mouse
Flo, IHC, IP
Unconjugated
50 µg/$217; 100 µg/$225
ITGAX / CD11c Antibody - 1:100 staining human Head and neck carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ITGAX / CD11c Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
ITGAX / CD11c Antibody - 1:100 staining human Head and neck carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ITGAX / CD11c Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
ITGAX / CD11c Antibody
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ITGAX / CD11c Rat anti-Mouse Monoclonal (223H7) Antibody
Mouse
Flo, IP
Unconjugated
100 µg/$353
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ITGAX / CD11c Mouse anti-Dog Monoclonal (Supernatant) (CA11.6A1) Antibody
Dog
Flo, IHC-Fr, IP
Unconjugated, Supernatant
2 ml/$471
Viewing 1-25 of 184 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).