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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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KRT4 / CK4 / Cytokeratin 4

keratin 4

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Name: keratin 4
Family/Subfamily: Keratin , not assigned-Keratin
Synonyms: KRT4, CK-4, CK4, Cytokeratin 4, Cytokeratin-4, K4, Keratin 4, Type-II keratin Kb4, CYK4, Keratin-4
Target Sequences: X07695 CAA30534.1 P19013

Publications (1)

1
A case of primary combined neuroendocrine carcinoma with squamous cell carcinoma in the upper gingiva. Mochizuki Y, Omura K, Sakamoto K, Nakanishi S, Satoh K, Marukawa E, Yamaguchi A. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2010 109:e34-9. (IHC) [PubMed:20303044]

Viewing 1-25 of 59 items
KRT4 / CK4 / Cytokeratin 4 Antibody - Anti-KRT4 / Cytokeratin 4 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Cancer
Mouse Monoclonal [clone 5H5] (IgG1,k) to Human KRT4 / CK4 / Cytokeratin 4
Human
ELISA, IF, IHC-P, WB
Unconjugated
50µg   $495.00
KRT4 / CK4 / Cytokeratin 4 Antibody - Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with KRT4 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
Rabbit Polyclonal to Human KRT4 / CK4 / Cytokeratin 4
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Mouse Monoclonal (IgG1) to Human KRT4 / CK4 / Cytokeratin 4
Human
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
1ml   $475.00
Select
Mouse Monoclonal (IgG1) to Human KRT4 / CK4 / Cytokeratin 4
Dog, Cat, Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
100µg   $560.00
Select
Mouse Monoclonal [clone 6B10] (IgG1) to Human KRT4 / CK4 / Cytokeratin 4
Dog, Cat, Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
0.1mg   $385.00
KRT4 / CK4 / Cytokeratin 4 Antibody - KRT4 / CK4 / Cytokeratin 4 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human KRT4 / CK4 / Cytokeratin 4
Rabbit, Dog, Bovine, Horse, Bat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
KRT4 / CK4 / Cytokeratin 4 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone CK-4] (IgG1) to Human KRT4 / CK4 / Cytokeratin 4
Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100µg   1ml   1mg/ml   $295.00
KRT4 / CK4 / Cytokeratin 4 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone CK-4] (IgG1) to Human KRT4 / CK4 / Cytokeratin 4
Rat, Human
IHC, IP
Magnetic beads Conjugated
100µg   $325.00
Select
Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
ELISA, IHC, WB
Unconjugated
100µg   $405.00
KRT4 / CK4 / Cytokeratin 4 Antibody - Immunochemical staining of human KRT4 in human esophagus with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
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Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
ICC, IF, IHC-P
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
KRT4 / CK4 / Cytokeratin 4 Antibody - 1:100 staining human lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
KRT4 / CK4 / Cytokeratin 4 Antibody - Immunohistochemistry of paraffin-embedded human cervical cancer using KRT4 Antibody at dilution of 1:100
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Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
ELISA, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
ELISA, WB
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
ELISA, WB
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
ELISA, WB
FITC Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal to Human KRT4 / CK4 / Cytokeratin 4
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   1mg/ml   $385.00
KRT4 / CK4 / Cytokeratin 4 Antibody - Immunohistochemistry of paraffin-embedded human cervical cancer tissue using KRT4 antibody.
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Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Mouse, Rat, Human
IHC, WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00
Select
Guinea pig Polyclonal to Human KRT4 / CK4 / Cytokeratin 4
Mouse, Human
IHC, WB
Unconjugated
100µl   $635.00
Select
Rabbit Polyclonal to Human KRT4 / CK4 / Cytokeratin 4
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
KRT4 / CK4 / Cytokeratin 4 Antibody - Western blot analysis of BT470 lysate, antibody was diluted at 500. Secondary antibody was diluted at 1:20000.
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Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Mouse, Rat, Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Mouse Monoclonal [clone 6B10] (IgG1) to Human KRT4 / CK4 / Cytokeratin 4
Human
IHC
Unconjugated
1ml   $590.00
KRT4 / CK4 / Cytokeratin 4 Antibody - Esophageal Squamous Carcinoma
Select
Mouse Monoclonal [clone ABT-CK4] (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
IHC
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
WB
Unconjugated
100µg   $605.00
KRT4 / CK4 / Cytokeratin 4 Antibody - Western blot analysis of Cytokeratin 4 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Select
Rabbit Polyclonal to Human KRT4 / CK4 / Cytokeratin 4
Mouse, Bovine, Rat, Human
WB
Unconjugated
100µl   1mg/ml   $245.00
KRT4 / CK4 / Cytokeratin 4 Antibody - Western blot analysis of extracts of various cell lines, using KRT4 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.
Select
Rabbit Polyclonal (IgG) to Human KRT4 / CK4 / Cytokeratin 4
Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00

Viewing 1-25 of 59 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).