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ITGA6/Integrin Alpha 6/CD49f

integrin, alpha 6

The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: integrin, alpha 6
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B
Target Sequences: NM_000210 NP_000201.2 P23229

Publications (8)

1
Reduced migration, altered matrix and enhanced TGFbeta1 signaling are signatures of mouse keratinocytes lacking Sdc1. Stepp MA, Liu Y, Pal-Ghosh S, Jurjus RA, Tadvalkar G, Sekaran A, Losicco K, Jiang L, Larsen M, Li L, Yuspa SH. Journal of cell science. 2007 120:2851-63. [PubMed:17666434] Related Antibodies: LS-C41344.
2
Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Horwitz KB, Dye WW, Harrell JC, Kabos P, Sartorius CA. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:5774-9. (IHC) [PubMed:18391223] [PMC:PMC2311360] Related Antibodies: LS-C41344.
3
Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z, Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G, Cordon-Cardo C, Pandolfi PP. Science signaling. 2009 2:ra2. [PubMed:19176516] [PMC:PMC2906144] Related Antibodies: LS-C41344.
4
Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo. Xu T, Xu Y, Liao CP, Lau R, Goldkorn A. Molecular cancer therapeutics. 2010 9:438-49. [PubMed:20124445] [PMC:PMC2820598] Related Antibodies: LS-C41344.
5
Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche. Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus MC, Tetta C, Bussolati B, Camussi G. Cancer research. 2011 71:5346-56. [PubMed:21670082] Related Antibodies: LS-C41344.
6
Suppressed prostate epithelial development with impaired branching morphogenesis in mice lacking stromal fibromuscular androgen receptor. Lai KP, Yamashita S, Vitkus S, Shyr CR, Yeh S, Chang C. Molecular endocrinology (Baltimore, Md.). 2012 26:52-66. [PubMed:22135068] [PMC:PMC3248327] Related Antibodies: LS-C41344.
7
Immunocytochemical stem cell markers can predict clinical stage of breast cancer. Pedro J Gutiérrez Diez, Yanrong Su, Jose Russo. Oncology reports. 2017 Sep;38:1507-1516. [Full Text Article] [PubMed:28714035] Related Antibodies: LS-A8769.
8
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Jo M, Eastman BM, Webb DL, Stoletov K, Klemke R, Gonias SL. Cancer research. 2010 70:8948-58. [PubMed:20940399] [PMC:PMC2970644] Related Antibodies: LS-C41344.
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☰ Filters
Antibodies (147)
Proteins (5)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (147)
Recombinant (3)
Sandwich (2)
ITGA6/Integrin Alpha 6/CD49f (154)
Human (123)
Mouse (51)
Rat (21)
Bat (14)
Bovine (15)
Chicken (7)
Cynomolgus (1)
Dog (26)
Guinea pig (7)
Hamster (14)
Horse (21)
Monkey (31)
Pig (12)
Sheep (3)
IHC (102)
IHC-Fr (19)
IHC-P (33)
WB (68)
Flo (59)
ELISA (24)
Func (1)
ICC (20)
IF (14)
IP (36)
Peptide-ELISA (1)
rabbit (73)
mouse (56)
goat (1)
rat (17)
Product Group
IHCPlus (30)
IgG (41)
IgG1 (23)
IgG1,k (7)
IgG2,k (7)
IgG2a (17)
IgG2a,k (1)
IgG2b (9)
monoclonal mc (73)
polyclonal pc (74)
129CT49.6.5 (5)
450-30A (4)
4C1 (1)
4F10 (4)
6B4 (1)
BQ16 (5)
GoH3 (3)
Mab-5A (3)
NKI-GoH3 (2)
96-Well Strip Plate (2)
AP Conjugated (12)
APC (1)
APC Conjugated (11)
Azide-free (7)
Biotin Conjugated (15)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (20)
HRP Conjugated (14)
PE Conjugated (16)
Preservative Free (1)
RPE Conjugated (4)
Unconjugated (53)
Internal (14)
N-Terminus (14)
aa1043-1072 (8)
aa903-1073 (8)
900-980 aa, C-terminal (1)
C-Terminus (1)
Cytoplasmic Domain (1)
aa1082-1110 (1)
aa324-620 (1)
aa50-100 (1)
aa565-872 (1)
aa750-800 (1)
aa923-972 (1)
aa93-148 (1)
light chain, Cleaved-Glu942 (1)
No (152)
Yes (2)
Cell Lysates (1)
Tissue Homogenates (2)
GST, N-terminus (1)
His-GST (1)
Myc-DDK (Flag) (3)
Human (3)
Mouse (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
ITGA6/Integrin Alpha 6/CD49f Antibody - Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (Internal) Antibody
Horse, Human
IHC, IHC-P
Unconjugated
50 µg/$460
ITGA6/Integrin Alpha 6/CD49f Antibody - Anti-ITGA6/Integrin Alpha 6/CD49f antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (aa324-620) (129CT49.6.5) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$525
ITGA6/Integrin Alpha 6/CD49f Antibody - Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ITGA6/Integrin Alpha 6/CD49f Antibody - Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
ITGA6/Integrin Alpha 6/CD49f Antibody - Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ITGA6/Integrin Alpha 6/CD49f Antibody - Anti-ITGA6 / CD49f antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (aa1043-1072) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
200 µl/$515
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ITGA6/Integrin Alpha 6/CD49f Rat anti-Human Monoclonal (RPE) (NKI-GoH3) Antibody
Human
Flo
RPE Conjugated
100 Tests/$456
ITGA6/Integrin Alpha 6/CD49f Antibody - MDA-MB-231 breast cancer cells were stained with anti-CD49f (clone GoH3) followed by DyLight 649 Goat anti-rat Ig secondary antibody (red), plus DAPI staining for nuclei (blue). Images were taken under 20x bin4 (Filter set: EX647/10x, Dichroic 665LP, EM 700/70x) at exposure 4s. Data provided by Er Liu and John Nolan, La Jolla Institute for Bioengineering.
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ITGA6/Integrin Alpha 6/CD49f Rat anti-Human Monoclonal (GoH3) Antibody
Mouse, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$266
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Rat Monoclonal (Mab-5A) Antibody
Rat
ELISA, Flo, IF, IHC, IHC-Fr
Unconjugated
0.25 mg/$450
Select
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Rat Monoclonal (RPE) (Mab-5A) Antibody
Rat
Flo
RPE Conjugated
100 Tests/$464
Select
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, WB
Unconjugated
100 µg/$498
ITGA6/Integrin Alpha 6/CD49f Antibody - Detection limit for recombinant GST tagged ITGA6 is approximately 0.1 ng/ml as a capture antibody.
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (4C1) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$407
ITGA6/Integrin Alpha 6/CD49f Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with CD49f Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ITGA6/Integrin Alpha 6/CD49f Rabbit anti-Human Polyclonal (aa1082-1110) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$381
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Mouse Monoclonal (4F10) Antibody
Mouse, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$642
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Chicken Monoclonal Antibody
Chicken
ICC, IHC, IP, WB
Unconjugated
100 µg/$713
Select
ITGA6/Integrin Alpha 6/CD49f Rat anti-Human Monoclonal Antibody
Mouse, Dog, Pig, Cynomolgus, Human
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$544; 200 µg/$736
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (Biotin) (BQ16) Antibody
Human
Flo, IHC, WB
Biotin Conjugated
100 µg/$386
ITGA6/Integrin Alpha 6/CD49f Antibody - Flow cytometry of ITGA6/Integrin Alpha 6/CD49f antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (FITC) (BQ16) Antibody
Human
Flo, IHC, WB
FITC Conjugated
120 Tests/$386
Select
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (RPE) (BQ16) Antibody
Human
Flo, IHC, WB
RPE Conjugated
120 Tests/$451
ITGA6/Integrin Alpha 6/CD49f Antibody - Western Blot (WB) analysis using Integrin alpha6 Monoclonal Antibody against 293, HepG2 cell lysate.
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal Antibody
Mouse, Dog, Bovine, Rat, Pig, Human
IF, WB
Unconjugated
50 µl/$342; 100 µl/$371
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (129CT49.6.5) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$614
Select
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (Azide-free) (HRP) (129CT49.6.5) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$767
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (AP) (129CT49.6.5) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
AP Conjugated
200 µl/$767
Select
ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal (APC) (129CT49.6.5) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$767
ITGA6/Integrin Alpha 6/CD49f Antibody - Western blot analysis of extracts of HepG2 cells.
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ITGA6/Integrin Alpha 6/CD49f Mouse anti-Human Monoclonal Antibody
Human
Flo, IF, IHC, WB
Unconjugated
100 µl/$333; 200 µl/$429
Viewing 1-25 of 154 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).