HES1 / HES-1

hes family bHLH transcription factor 1

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

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Products

Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

HES1 / HES-1 (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (2)

His (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (8)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human HES1 / HES-1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65833

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.4 kDa

Price:

20 µg/$1,107

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Human HES1 / HES-1 Protein (Recombinant GST, N-terminus) (aa36-142) - LS-G58898

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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Human HES1 / HES-1 Protein (Recombinant GST, N-terminus) (aa201-280) - LS-G58899

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human HES1 / HES-1 Protein (Recombinant His-T7) (aa21-251) - LS-G26070

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.3 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human HES1 / HES-1 Protein (Recombinant GST) (Full Length) - LS-G28921

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55.7 kDa

Price:

2 µg/$439

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Human HES1 / HES-1 Protein (Recombinant His, N-Terminal) - LS-G144357

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

29.4 kDa

Price:

50 µg/$419

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Human HES1 / HES-1 Protein (Recombinant His) (aa2-280) - LS-G3855

Source:

E. coli

Tag:

His

Molecular Weight:

~35kDa (SDS-PAGE)

Price:

50 µg/$793; 10 µg/$414

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Human HES1 / HES-1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76378

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.4 kDa

Price:

20 µg/$150

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HES1 / HES-1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115914

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.4 kDa

Price:

100 µg/$494

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