Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
|Gene Name:||Kruppel-like factor 17|
|Synonyms:||KLF17, Kruppel-like factor 17, Novel zinc-finger protein, Zfp393, ZNF393, RP4-675G8.1, Zinc finger protein 393, Krueppel-like factor 17|
|Target Sequences:||Q5JT82 Q5JT82|
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