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CARD16 / COP

caspase recruitment domain family, member 16

Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.

Gene Name: caspase recruitment domain family, member 16
Synonyms: CARD16, Caspase-1 inhibitor COP, COP1, CARD only protein, Pseudo-ICE
Target Sequences: NP_001017534.1 Q5EG05

☰ Filters
Antibodies (24)
Proteins (8)
Over-Expression Lysate (4)
Primary (24)
Recombinant (4)
CARD16 / COP (32)
Human (24)
WB (23)
Flo (8)
ELISA (14)
IF (2)
Peptide-ELISA (1)
rabbit (15)
mouse (8)
goat (1)
IgG (15)
IgG2b,k (7)
monoclonal mc (7)
polyclonal pc (17)
AP Conjugated (3)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (6)
aa37-65 (8)
aa1-98 (1)
aa85-97 (1)
No (32)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$614
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (Biotin) Antibody
Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$767
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$767
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$767
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (AP) Antibody
Human
ELISA, Flo, WB
AP Conjugated
200 µl/$767
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (APC) Antibody
Human
ELISA, Flo, WB
APC Conjugated
200 µl/$767
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) (PE) Antibody
Human
ELISA, Flo, WB
PE Conjugated
200 µl/$767
Select
CARD16 / COP Mouse anti-Human Monoclonal (aa1-98) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$582
Select
CARD16 / COP Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$734
Select
CARD16 / COP Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$734
Select
CARD16 / COP Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$734
Select
CARD16 / COP Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$734
Select
CARD16 / COP Mouse anti-Human Monoclonal (AP) Antibody
Human
ELISA, WB
AP Conjugated
100 µl/$734
Select
CARD16 / COP Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$734
CARD16 / COP Antibody - COP1 Antibody western blot of CEM,A549 cell line lysates (35 ug/lane). The COP1 antibody detected the COP1 protein (arrow).
Select
CARD16 / COP Rabbit anti-Human Polyclonal (aa37-65) Antibody
Human
Flo, WB
Unconjugated
400 µl/$376
Select
CARD16 / COP Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$582
CARD16 / COP Antibody - CARD16 / COP antibody immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing mitochondrial staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
Select
CARD16 / COP Goat anti-Human Polyclonal (aa85-97) Antibody
Human
IF, Peptide-ELISA
Unconjugated
100 µg/$451
Select
CARD16 / COP Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$622
Select
CARD16 / COP Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$774
Select
CARD16 / COP Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$774
Select
CARD16 / COP Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$774
Select
CARD16 / COP Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$774
Select
CARD16 / COP Rabbit anti-Human Polyclonal (AP) Antibody
Human
WB
AP Conjugated
100 µl/$774
Select
CARD16 / COP Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$774
CARD16 / COP Protein - Purified recombinant protein CARD16 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
10.6 kDa
20 µg/$1,005
Viewing 1-25 of 32 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).