Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).
|Gene Name:||solute carrier family 5 (sodium/choline cotransporter), member 7|
|Family/Subfamily:||Transporter , Solute:sodium symporter|
|Synonyms:||SLC5A7, CHT, CHT1, Choline transporter, HCHT|
|Target Sequences:||NM_021815 NP_068587.1 Q9GZV3|
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