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MUC4

mucin 4, cell surface associated

May play a role in tumor progression. Ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation. Has anti-adhesive properties. Seems to alter cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and in its ability to act as an intramembrane ligand for ERBB2. Plays an important role in cell proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. The MUC4-ERBB2 complex causes site-specific phosphorylation of the ERBB2 'Tyr-1248'. In polarized epithelilal cells segragates ERBB2 and other ERBB receptors and prevents ERBB2 from acting as a coreceptor. The interaction with ERBB2 leads to enhanced expression of CDKN1B. The formation of a MUC4-ERBB2-ERBB3-NRG1 complex leads to down-regulation of CDKN1B, resulting in repression of apoptosis and stimulation of proliferation.

Gene Name: mucin 4, cell surface associated
Family/Subfamily: Mucin , not assigned-Mucin
Synonyms: MUC4, ASGP, HSA276359, Mucin-4, Testis mucin, Tracheobronchial mucin, Ascites sialoglycoprotein, MUC-4, Mucin 4, tracheobronchial
Target Sequences: NM_018406 Q99102

☰ Filters
Products
ELISA Kits (12)
Sandwich (11)
Sandwich CLIA (1)
MUC4 (12)
Human (5)
Mouse (2)
Rat (1)
Chicken (1)
Monkey (1)
Pig (1)
Sheep (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (9)
No (12)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (8)
Serum (8)
Tissue Homogenates (5)
MUC4 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
MUC4 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$783
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$627
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
MUC4 ELISA Kit
Select
Sandwich
96-Well Microplate
Pig
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$870
MUC4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$818
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).