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PICK1

protein interacting with PRKCA 1

Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

Gene Name: protein interacting with PRKCA 1
Synonyms: PICK1, DJ1039K5, PRKCABP, Protein interacting with PRKCA, PRKCA-binding protein, PICK
Target Sequences: NM_012407 NP_036539.1 Q9NRD5

Publications (1)

1
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1. Bassan M, Liu H, Madsen KL, Armsen W, Zhou J, Desilva T, Chen W, Paradise A, Brasch MA, Staudinger J, Gether U, Irwin N, Rosenberg PA. The European journal of neuroscience. 2008 27:66-82. [PubMed:18184314]

☰ Filters
Antibodies (42)
Proteins (19)
ELISA Kits (9)
Custom (5)
Over-Expression Lysate (10)
Primary (42)
Recombinant (9)
Sandwich (4)
PICK1 (70)
Human (35)
Mouse (31)
Rat (14)
Bovine (2)
Chicken (2)
Dog (1)
Hamster (1)
Horse (1)
Monkey (3)
Pig (1)
Porcine (1)
Rabbit (2)
Sheep (1)
Xenopus (1)
IHC (9)
IHC-P (1)
WB (40)
ELISA (21)
IF (4)
IP (1)
Peptide-ELISA (1)
rabbit (41)
goat (1)
Product Group
IHCPlus (1)
IgG (24)
polyclonal pc (42)
96-Well Strip Plate (9)
AP Conjugated (2)
APC (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (17)
aa1-30 (8)
aa24-229 (8)
aa286-316 (8)
C-Terminus (5)
aa100-110 (1)
No (70)
Cell Lysates (1)
Plasma (3)
Serum (3)
Tissue Homogenates (1)
GST (2)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (13)
Human (13)
Mouse (1)
293T Cells (5)
E. coli (4)
HEK 293 Cells (8)
Wheat Germ Extract (2)
Purified (2)
PICK1 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PICK1 Goat anti-Human Polyclonal (aa100-110) Antibody
Xenopus, Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
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PICK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$396
PICK1 Antibody - Immunohistochemistry of paraffin-embedded human colon tissue.
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PICK1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
PICK1 Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using PICK1 Antibody at dilution of 1:100
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PICK1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$284; 100 µg/$351
PICK1 Antibody - Western blot. All lanes: Acid-sensing ion channel 3 antibody at 2 ug/ml+mouse brain tissue. Secondary antibody: goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PICK1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$284; 100 µg/$351
PICK1 Antibody - Western blot. All lanes: Acid-sensing ion channel 3 antibody at 2 ug/ml+mouse brain tissue. Secondary antibody: goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PICK1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$284; 100 µg/$351
PICK1 Antibody - Western blot. All lanes: Acid-sensing ion channel 3 antibody at 2 ug/ml+mouse brain tissue. Secondary antibody: goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PICK1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$284; 100 µg/$351
PICK1 Antibody - Western blot analysis of rat brain lysates using PICK1 antibody. The lane on the left is treated with the antigen-specific peptide.
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PICK1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
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PICK1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC
Unconjugated
60 µl/$278; 120 µl/$338; 200 µl/$440
Select
PICK1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
Select
PICK1 Rabbit anti-Human Polyclonal (aa286-316) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$614
Select
PICK1 Rabbit anti-Human Polyclonal (aa286-316) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa286-316) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa286-316) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa286-316) (AP) Antibody
Mouse, Human
ELISA, WB
AP Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa286-316) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa286-316) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$614
Select
PICK1 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa1-30) (AP) Antibody
Mouse, Human
ELISA, WB
AP Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$767
Select
PICK1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$347
Viewing 1-25 of 70 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).