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P2RX2 / P2X2
purinergic receptor P2X, ligand-gated ion channel, 2
Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K+ recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
| Gene Name: | purinergic receptor P2X, ligand-gated ion channel, 2 |
| Family/Subfamily: | Ion Channel , P2X receptor |
| Synonyms: | P2RX2, ATP receptor, p2X2, p2X Receptor, subunit 2, Purinergic receptor, p2RX2, p2X receptor 2, p2X purinoceptor 2, p2X2 purinoceptor |
| Target Sequences: | NM_012226 NP_036358.2 Q9UBL9 |
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