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RNF34

ring finger protein 34, E3 ubiquitin protein ligase

E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis (PubMed:15069192). May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway (PubMed:19690332). Negatively regulates p53/TP53 through its direct ubiquitination and targeting to proteasomal degradation (PubMed:17121812). Indirectly, may also negatively regulate p53/TP53 through ubiquitination and degradation of SFN (PubMed:18382127). Mediates PPARGC1A proteasomal degradation probably through ubiquitination thereby indirectly regulating the metabolism of brown fat cells (PubMed:22064484). Possibly involved in innate immunity, through 'Lys-48'-linked polyubiquitination of NOD1 and its subsequent proteasomal degradation (PubMed:25012219).

Gene Name: ring finger protein 34, E3 ubiquitin protein ligase
Synonyms: RNF34, CARP1, Caspase regulator CARP1, CARP-1, FYVE-RING finger protein Momo, HRFI, RFI, RIF, RIFF, RING finger protein 34, RING finger protein RIFF
Target Sequences: NM_025126 NP_079402.2 Q969K3

☰ Filters
Antibodies (27)
cDNAs (15)
Proteins (9)
cDNA Clone (1)
Expression-Ready ORF Clone (14)
Over-Expression Lysate (6)
Primary (27)
Recombinant (3)
RNF34 (51)
Human (27)
Mouse (2)
Rat (2)
Bat (1)
Bovine (6)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (4)
Hamster (2)
Horse (2)
Monkey (5)
Orangutan (3)
Rabbit (6)
IHC (5)
IHC-P (4)
WB (24)
ELISA (17)
IF (1)
Peptide-ELISA (2)
rabbit (25)
goat (2)
Product Group
IHCPlus (2)
IgG (19)
polyclonal pc (27)
AP Conjugated (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (13)
aa283-311 (8)
aa143-192 (4)
aa1-373 (1)
aa299-311 (1)
aa3-14 (1)
No (51)
DDK (Flag), C-terminus (1)
DDK (Flag), N-terminus (1)
GFP, C-terminus (2)
GFP, N-terminus (1)
GST (1)
HA, C-terminus (1)
HA, N-terminus (1)
His (1)
His, C-terminus (1)
His, N-terminus (1)
Myc, C-terminus (1)
Myc, N-terminus (1)
Myc-DDK (Flag) (7)
OFP, C-terminus (1)
OFP, N-terminus (1)
Untagged (2)
Mouse (15)
Lentiviral (1)
Mammalian (13)
Human (6)
293T Cells (3)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (2)
RNF34 Antibody - Anti-RNF34 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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RNF34 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$665
RNF34 Antibody - Anti-RNF34 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
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RNF34 Goat anti-Human Polyclonal (aa3-14) Antibody
Rabbit, Mouse, Bovine, Rat, Hamster, Horse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$585
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RNF34 Rabbit anti-Human Polyclonal (aa1-373) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$605
Select
RNF34 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$794
Select
RNF34 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$794
Select
RNF34 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$794
Select
RNF34 Rabbit anti-Human Polyclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$794
Select
RNF34 Rabbit anti-Human Polyclonal (AP) Antibody
Human
ELISA, WB
AP Conjugated
100 µl/$794
RNF34 Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer at dilution 1:100
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RNF34 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$251; 100 µl/$285
Select
RNF34 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$376
RNF34 Antibody - Immunohistochemistry of paraffin-embedded human prostate cancer at dilution 1:100
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RNF34 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$251; 100 µl/$285
Select
RNF34 Rabbit anti-Human Polyclonal (aa283-311) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$614
Select
RNF34 Rabbit anti-Human Polyclonal (aa283-311) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$767
Select
RNF34 Rabbit anti-Human Polyclonal (aa283-311) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$767
Select
RNF34 Rabbit anti-Human Polyclonal (aa283-311) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$767
Select
RNF34 Rabbit anti-Human Polyclonal (aa283-311) (AP) Antibody
Human
ELISA, WB
AP Conjugated
200 µl/$767
Select
RNF34 Rabbit anti-Human Polyclonal (aa283-311) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$767
Select
RNF34 Rabbit anti-Human Polyclonal (aa283-311) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$767
Select
RNF34 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$278; 120 µl/$338; 200 µl/$440
RNF34 Antibody - RNF34 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF34 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Rabbit, Guinea pig, Bovine, Human, Monkey
WB
Unconjugated
100 µl/$434
RNF34 Antibody - RNF34 antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RNF34 Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody
Rabbit, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$459
RNF34 Antibody - RNF34 Antibody western blot of HeLa cell line lysates (35 ug/lane). The RNF34 antibody detected the RNF34 protein (arrow).
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RNF34 Rabbit anti-Human Polyclonal (aa283-311) Antibody
Human
WB
Unconjugated
400 µl/$376
RNF34 Antibody - Western blot analysis of extracts of various cells.
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RNF34 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
RNF34 Antibody
Select
RNF34 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$276; 100 µl/$311
Select
RNF34 Goat anti-Human Polyclonal (aa299-311) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
Peptide-ELISA
Unconjugated
100 µg/$374
Viewing 1-25 of 51 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).