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CST3 / Cystatin C

cystatin C

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein.

Gene Name: cystatin C
Synonyms: CST3, ARMD11, BA218C14.4 (cystatin C), Cystatin-3, Cystatin 3, Cystatin C, Cystatin-C, Gamma-trace, Post-gamma-globulin
Target Sequences: NM_000099 NP_000090.1 P01034

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Antibodies (232)
ELISA Kits (50)
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CST3 / Cystatin C (352)
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CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
CST3 / Cystatin C Goat anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$615
CST3 / Cystatin C ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.3 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$537
CST3 / Cystatin C ELISA Kit
Select
Sandwich
96-Well Microplate
Canine
10.24 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$761
CST3 / Cystatin C ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$559
CST3 / Cystatin C ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$744
CST3 / Cystatin C Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CST3 / Cystatin C Mouse anti-Human Monoclonal (2C8) Antibody
Human
IHC-P, WB
Unconjugated
50 µl/$485
CST3 / Cystatin C ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$889
CST3 / Cystatin C Protein - Recombinant Cystatin 3 By SDS-PAGE
Select
E. coli
6His, N-terminus
14.5 kDa
10 µg/$265; 50 µg/$384; 100 µg/$612; 200 µg/$765; 1 mg/$1,748
CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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CST3 / Cystatin C Mouse anti-Human Monoclonal (aa95-122) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$515
CST3 / Cystatin C Antibody - Anti-CST3 / Cystatin C antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
CST3 / Cystatin C Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
Select
CST3 / Cystatin C Rabbit anti-Mouse Monoclonal (Preservative Free) (041) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
50 µl/$290; 100 µl/$350
CST3 / Cystatin C Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CST3 / Cystatin C Sheep anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
CST3 / Cystatin C Antibody - Western blot of recombinant CST3 / Cystatin C.
Select
CST3 / Cystatin C Rabbit anti-Pig Polyclonal (aa42-127) Antibody
Pig
WB
Unconjugated
100 µl/$307; 200 µl/$352; 500 µl/$503; 1 ml/$584
CST3 / Cystatin C Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CST3 / Cystatin C Sheep anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
CST3 / Cystatin C Antibody - Western Blot; Sample: Recombinant CST3, Human.
Select
CST3 / Cystatin C Mouse anti-Human Monoclonal (APC) Antibody
Rat, Human
WB
APC Conjugated
200 µl/$433; 500 µl/$716; 1 ml/$833
CST3 / Cystatin C Antibody - IHC-P: Cystatin C antibody testing of human breast cancer tissue
Select
CST3 / Cystatin C Rabbit anti-Human Polyclonal (aa45-63) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$480
CST3 / Cystatin C Antibody - Immunohistochemistry of paraffin-embedded human prostate.
Select
CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
Select
CST3 / Cystatin C Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, ID, IHC, IP, WB
Unconjugated
1 mg/$386
Select
CST3 / Cystatin C Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, ID, IHC, IP, WB
Unconjugated
1 ml/$232
CST3 / Cystatin C Antibody - Immunohistochemical analysis of human-kidney tissue. Anti-Cystatin C at 1:200 (4°C, overnight). Antigen retrieval - Sodium Citrate pH6 (>98°C, 20min). Secondary - 1:200 (room temp, 30min). Negative control - Secondary only
Select
CST3 / Cystatin C Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µl/$277; 100 µl/$308; 200 µl/$374
CST3 / Cystatin C Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
CST3 / Cystatin C Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
CST3 / Cystatin C Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CST3 / Cystatin C Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
Select
CST3 / Cystatin C Mouse anti-Human Monoclonal (3B6) Antibody
Human
ELISA, IF, IHC-P, WB
Unconjugated
20 µl/$242; 60 µl/$278; 120 µl/$338; 200 µl/$440
Viewing 1-25 of 352 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).