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Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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PHACTR4

Phosphatase And Actin Regulator 4

Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway.

Gene Name: Phosphatase And Actin Regulator 4
Synonyms: PHACTR4, RP11-442N24__A.1
Target Sequences: NM_023923 NP_076412.3 Q8IZ21


Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Human
ELISA, IF, WB
Unconjugated
100µg   $335.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Human
ELISA, ICC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
PHACTR4 Antibody
Select
Rabbit Polyclonal to Human PHACTR4
Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $265.00
PHACTR4 Antibody
Select
Rabbit Polyclonal to Human PHACTR4
Human
ELISA, IHC, WB
Unconjugated
100µg   1mg/ml   $265.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Mouse, Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Mouse, Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Mouse, Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Mouse, Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Mouse, Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Mouse, Human
ELISA, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Human
ELISA, WB
Unconjugated
50µg   1mg/ml   $265.00; 100µg   1mg/ml   $325.00
PHACTR4 Antibody - Western blot analysis of extracts of rat Heart cells using PHACTR4 antibody. The lane on the left is treated with the antigen-specific peptide.
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Rat, Human
ELISA, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
PHACTR4 Antibody - Western blot analysis of the lysates from HeLa cells using PHACTR4 antibody.
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Human
Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
PHACTR4 Antibody - Western blot of lysate from human kidney tissue lysate, using PHAR4 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
Select
Rabbit Polyclonal to Human PHACTR4
Mouse, Human
WB
Unconjugated
400µl   $325.00
PHACTR4 Antibody - Immunochemical staining of human PHACTR4 in human rectum with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
Select
Rabbit Polyclonal (IgG) to Human PHACTR4
Human
IHC-P
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
Viewing 1-16 of 16 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).