Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Caspases are produced as zymogens composed of a prodomain plus a large subunit and a small subunit, and require proteolytic processing at internal aspartate residues to generate an active dimeric enzyme. Caspase-13 induces cell death when overexpressed in mammalian cells and is activated by caspase-8, the initiating caspase in the apoptotic cascade. FROM NCBI: DISCONTINUED: LocusID 8628 was defined by AF078533 which has been reported to be (PubMed ID: 11478774) of bovine origin. There is no evidence for this sequence in human.
|Gene Name:||CASP13 / Caspase 13|
|Family/Subfamily:||Protease , Cysteine C14|
|Target Sequences:||AF078533 AAC28380.1|
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