MPO / Myeloperoxidase

myeloperoxidase

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains (12 kD) and 2 heavy chains (60 kD). This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. It is released in a degranulation process in response to bursts of oxygen consumption, which also forms H2O2. MPO and H2O2 form a complex that oxidases a large variety of substances some of which have microbicidal effects. The gene for MPO is translocated in patients with acute promyelocytic leukemia and is mutated in hereditary MPO deficiency.

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Products

Proteins (16)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (3)

Recombinant (12)

Target

MPO / Myeloperoxidase (16)

Publications

No (16)

Tag

10His, C-terminus (2)

6His, N-terminus (2)

GST, N-terminus (1)

His (4)

His, C-Terminal (1)

His, N-Terminal (1)

His,C-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (10)

Mouse (4)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (5)

Human (1)

Human Cells (1)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (5)

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Human MPO / Myeloperoxidase Protein (Over-Expression Lysate 6His, N-terminus) (Ala49-Ser745) - LS-G26801

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

82 kDa

Price:

100 µg/$298

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Mouse MPO / Myeloperoxidase Protein (Recombinant His,C-terminus) (Met16-Thr718) - LS-G139885

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

81.1 kDa

Price:

10 µg/$288; 50 µg/$436

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Human MPO / Myeloperoxidase Protein (Recombinant 10His, C-terminus) (Ala49-Ser745) - LS-G51904

Source:

Human Cells

Tag:

10His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.3kD

Price:

10 µg/$243; 50 µg/$277; 500 µg/$395; 1 mg/$505

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Mouse MPO / Myeloperoxidase Protein (Recombinant His, C-Terminal) (Met16-Thr718) - LS-G55706

Source:

Human

Tag:

His, C-Terminal

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

81.1kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,484; 1 mg/$2,157

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Human MPO / Myeloperoxidase Protein (Recombinant GST, N-terminus) (aa646-745) - LS-G59269

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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Human MPO / Myeloperoxidase Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70820

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.7 kDa

Price:

20 µg/$1,107

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Human MPO / Myeloperoxidase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88066

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.7 kDa

Price:

20 µg/$215

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Human MPO / Myeloperoxidase Protein (Recombinant His, N-Terminal) (Ala49-Ser745) - LS-G97012

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~82 kDa (90-100 kDa reducing conditions)

Price:

10 µg/$289

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Mouse MPO / Myeloperoxidase Protein (Recombinant His) (aa139-252) - LS-G12473

Source:

E. coli

Tag:

His

Molecular Weight:

14.4 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human MPO / Myeloperoxidase Protein (Recombinant His) (aa165-278) - LS-G12474

Source:

E. coli

Tag:

His

Molecular Weight:

14.4 kDa

Price:

10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723

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Mouse MPO / Myeloperoxidase Protein (Recombinant His) (aa253-718) - LS-G12475

Source:

E. coli

Tag:

His

Molecular Weight:

54.6 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Rat MPO / Myeloperoxidase Protein (Recombinant His-T7) (aa134-263) - LS-G12477

Source:

E. coli

Tag:

His-T7

Molecular Weight:

19.0 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

Select

Human MPO / Myeloperoxidase Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Ala49-Ser745) - LS-G26936

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

82 kDa

Price:

200 µl/$283

Select

Human MPO / Myeloperoxidase Protein (Recombinant 10His, C-terminus) (Ala49-Ser745) - LS-G140290

Source:

Mammalian Cells

Tag:

10His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.3 kDa

Price:

10 µg/$317; 50 µg/$407

Select

Human MPO / Myeloperoxidase Protein (Recombinant His) (aa591-745) - LS-G140991

Source:

E. coli

Sequence Length:

154 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

17.05 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

Select

MPO / Myeloperoxidase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123312

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.7 kDa

Price:

100 µg/$710

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