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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MPO / Myeloperoxidase

myeloperoxidase

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains (12 kD) and 2 heavy chains (60 kD). This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. It is released in a degranulation process in response to bursts of oxygen consumption, which also forms H2O2. MPO and H2O2 form a complex that oxidases a large variety of substances some of which have microbicidal effects. The gene for MPO is translocated in patients with acute promyelocytic leukemia and is mutated in hereditary MPO deficiency.

Gene Name: myeloperoxidase
Synonyms: MPO, Myeloperoxidase precursor, Myeloperoxidase
Target Sequences: NM_000250 NP_000241.1 P05164

Publications (3)

1
The glycosylation of myeloperoxidase. Ravnsborg T, Houen G, Hjrup P. Biochimica et biophysica acta. 2010 1804:2046-53. (ELISA; Human) [PubMed:20621206] Related Antibodies: LS-C41696.
2
Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction in a rat model of alcoholic liver disease: role of zinc deficiency. Sun Q, Zhong W, Zhang W, Zhou Z. American journal of physiology. Gastrointestinal and liver physiology. 2016 310:G205-14. (IHC; Human) [Full Text Article] [PubMed:26585415] [PMC:PMC4971814] Related Antibodies: LS-B6699.
3
Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice. Iracheta-Vellve A, Petrasek J, Gyogyosi B, Bala S, Csak T, Kodys K, Szabo G. Liver international : official journal of the International Association for the Study of the Liver. 2017 July;37:968-973. [Full Text Article] [PubMed:28345165] [PMC:PMC5479767] Related Antibodies: LS-B4741.

Viewing 1-25 of 235 items
MPO / Myeloperoxidase Antibody - Anti-MPO / Myeloperoxidase antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Select
Cancer
Rabbit Polyclonal (IgG) to Human MPO / Myeloperoxidase
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
0.1ml   $485.00
MPO / Myeloperoxidase Antibody - Anti-MPO / Myeloperoxidase antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
Cancer
Mouse Monoclonal [clone 9B12G7] (IgG1) to Human MPO / Myeloperoxidase
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µl   $285.00
MPO / Myeloperoxidase Antibody - Anti-MPO / Myeloperoxidase antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer
Mouse Monoclonal [clone 3E11] (IgG2b,k) to Human MPO / Myeloperoxidase
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $425.00
MPO / Myeloperoxidase Antibody - Anti-MPO / Myeloperoxidase antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Rabbit Polyclonal (IgG) to Human MPO / Myeloperoxidase
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
250µl   $555.00
MPO / Myeloperoxidase Antibody - Anti-MPO / Myeloperoxidase antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
Select
Rabbit Polyclonal to Human MPO / Myeloperoxidase
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50µl   85mg/ml   $425.00
MPO / Myeloperoxidase Antibody - Anti-MPO / Myeloperoxidase antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human MPO / Myeloperoxidase
Human
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
500µg   $425.00
MPO / Myeloperoxidase Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Mouse MPO / Myeloperoxidase
Mouse, Rat, Human
IF, IHC
Unconjugated
60µl   0.81mg/ml   $425.00
MPO / Myeloperoxidase Antibody - Anti-MPO / Myeloperoxidase antibody IHC of human spleen, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
Rabbit Polyclonal (IgG) to Human MPO / Myeloperoxidase
Human
IHC, IHC-P, IP, WB
Unconjugated
50µl   $425.00
MPO / Myeloperoxidase Antibody - Western blot of recombinant MPO / Myeloperoxidase.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse MPO / Myeloperoxidase
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $285.00; 500µl   0.5mg/ml   $415.00; 1ml   0.5mg/ml   $485.00
MPO / Myeloperoxidase Antibody
Select
Rabbit Polyclonal to Mouse MPO / Myeloperoxidase
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $285.00; 500µl   0.5mg/ml   $415.00; 1ml   0.5mg/ml   $485.00
MPO / Myeloperoxidase Antibody - MPO / Myeloperoxidase antibody Western blot of 293T Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human MPO / Myeloperoxidase
Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
Select
Mouse Monoclonal [clone 2D4] (IgG1) to Mouse MPO / Myeloperoxidase
Mouse, Rat
Flo, IF, IHC, IHC-Fr
FITC Conjugated
100µg   0.1mg/ml   $800.00
Select
Rabbit Polyclonal (IgG) to Human MPO / Myeloperoxidase
Human
ELISA, IP, WB
Unconjugated
1ml   $455.00
Select
Mouse Monoclonal [clone 2A11] (IgG2a) to Human MPO / Myeloperoxidase
Human
ELISA
Unconjugated
0.2mg   $395.00
Select
Mouse Monoclonal [clone 8F4] (IgG1) to Mouse MPO / Myeloperoxidase
Mouse, Rat
Flo, IHC, IHC-Fr
Unconjugated
100µg   $650.00
Select
Mouse Monoclonal [clone 8F4] (IgG1) to Mouse MPO / Myeloperoxidase
Mouse
Flo, IHC, IHC-Fr
FITC Conjugated
100µg   0.1mg/ml   $740.00
Select
Human Polyclonal (IgG) to Human MPO / Myeloperoxidase
Human
ELISA, IF
Unconjugated
2ml   $405.00
Select
Mouse Monoclonal [clone 4A4] (IgG2b) to Human MPO / Myeloperoxidase
Human
ELISA
Unconjugated
1mg   $860.00
Select
Mouse Monoclonal [clone 2A11] (IgG2a) to Human MPO / Myeloperoxidase
Human
ELISA
Unconjugated
1mg   $860.00
Select
Mouse Monoclonal [clone 266-6K1] (IgG1) to Human MPO / Myeloperoxidase
Human
WB
Unconjugated
100µg   $710.00
Select
Mouse Monoclonal [clone 2C7] (IgG1) to Human MPO / Myeloperoxidase
Human
Flo
FITC Conjugated
0.1mg   $365.00
Select
Mouse Monoclonal [clone 2C7] (IgG1) to Human MPO / Myeloperoxidase
Human
ELISA, Flo, IHC, IHC-Fr, IHC-P
Unconjugated
20µg   $225.00; 0.2mg   1mg/ml   $395.00
Select
Rabbit Polyclonal to Human MPO / Myeloperoxidase
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100µg   $325.00
Select
Rabbit Polyclonal (IgG) to Human MPO / Myeloperoxidase
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100µg   $530.00
MPO / Myeloperoxidase Antibody - IHC-P: Myeloperoxidase antibody testing of human liver cancer tissue
Select
Rabbit Polyclonal (IgG) to Human MPO / Myeloperoxidase
Hamster, Human
IHC, IHC-P, WB
Unconjugated
100µg   $435.00

Viewing 1-25 of 235 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).