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The receptor for hyaluronan mediated motility has been reported to mediate migration, transformation, and metastatic spread of murine fibroblasts. In human, it is expressed as an intracellular protein in breast cancer cells. No correlation between the level of HMMR mRNA and protein expression with known metastatic/malignant potential of the tumor cell lines was observed.
Gene Name: | hyaluronan-mediated motility receptor (RHAMM) |
Synonyms: | HMMR, CD168, CD168 antigen, RHAMM, IHABP |
Target Sequences: | NM_012484 NP_036616.2 O75330 |
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