Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold.
|Gene Name:||tonsoku-like, DNA repair protein|
|Synonyms:||TONSL, I-kappa-B-related protein, IkappaBR, IKBR, NFKBIL2, Tonsoku-like protein|
|Target Sequences:||NM_013432 NP_038460.4 Q96HA7|
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.