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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KCNH2 / HERG

potassium voltage-gated channel, subfamily H (eag-related), member 2

Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.

Gene Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Family/Subfamily: Ion Channel , Potassium channel - Eag-related
Synonyms: KCNH2, Eag homolog, HERG-1, ERG1, HERG, KV11.1, M-erg1, H-ERG, HERG1, SQT1, LQT2, Merg1, Eag-related protein 1, ERG-1
Target Sequences: NM_000238 NP_000229.1 Q12809

Publications (2)

1
Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether--go-go-Related Gene. Roti EC, Myers CD, Ayers RA, Boatman DE, Delfosse SA, Chan EK, Ackerman MJ, January CT, Robertson GA. The Journal of biological chemistry. 2002 277:47779-85. [PubMed:12270925]
2
Cardiac IKr channels minimally comprise hERG 1a and 1b subunits. Jones EM, Roti Roti EC, Wang J, Delfosse SA, Robertson GA. The Journal of biological chemistry. 2004 279:44690-4. [PubMed:15304481]

Viewing 1-25 of 42 items
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   0.9mg/ml   $425.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   0.9mg/ml   $425.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human KCNH2 / HERG
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human KCNH2 / HERG
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human KCNH2 / HERG
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human KCNH2 / HERG
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human KCNH2 / HERG
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
KCNH2 / HERG Antibody - Anti-KCNH2 / Kv11.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human KCNH2 / HERG
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
KCNH2 / HERG Antibody
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Rabbit Polyclonal (IgG) to Human KCNH2 / HERG
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $265.00
KCNH2 / HERG Antibody - KCNH2 / Kv11.1 antibody Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Mouse KCNH2 / HERG
Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $365.00
KCNH2 / HERG Antibody - Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.
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Rabbit Polyclonal to Human KCNH2 / HERG
Human
Flo, WB
Unconjugated
400µl   $325.00
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Rabbit Polyclonal to Human KCNH2 / HERG
Human
ELISA, IHC, WB
Unconjugated
50µg   $285.00; 100µg   1mg/ml   $355.00
KCNH2 / HERG Antibody - Immunohistochemistry image of paraffin-embedded human heart tissue at a dilution of 1:100
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Rabbit Polyclonal (IgG) to Human KCNH2 / HERG
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50µg   $285.00; 100µg   $385.00
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Rabbit Polyclonal (IgG) to Human KCNH2 / HERG
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
HRP Conjugated
100µl   $830.00
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Rabbit Polyclonal (IgG) to Human KCNH2 / HERG
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
Biotin Conjugated
100µl   $830.00
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Rabbit Polyclonal (IgG) to Human KCNH2 / HERG
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
FITC Conjugated
100µl   $830.00
Select
Rabbit Polyclonal (IgG) to Human KCNH2 / HERG
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
AP Conjugated
100µl   $830.00
Select
Rabbit Polyclonal (IgG) to Human KCNH2 / HERG
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
PE Conjugated
100µl   $830.00
Select
Rabbit Polyclonal (IgG) to Human KCNH2 / HERG
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
APC Conjugated
100µl   $830.00

Viewing 1-25 of 42 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).