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PCGF6

polycomb group ring finger 6

Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Gene Name: polycomb group ring finger 6
Synonyms: PCGF6, MBLR, Polycomb group ring finger 6, RING finger protein 134, RNF134
Target Sequences: NM_032154 NP_115530.2 Q9BYE7

Publications (1)

1
PRC1 Catalytic Activity Is Central to Polycomb System Function. Neil P Blackledge, Nadezda A Fursova, Jessica R Kelley, Miles K Huseyin, Angelika Feldmann, Robert J Klose. Molecular cell. 2020 Feb;77:857-874e9. [Full Text Article] [PubMed:31883950] [PMC:PMC7033600]

☰ Filters
Antibodies (21)
Proteins (6)
ELISA Kits (4)
Custom (2)
Over-Expression Lysate (4)
Primary (21)
Recombinant (2)
Sandwich (2)
PCGF6 (31)
Human (22)
Mouse (3)
Rat (2)
Monkey (4)
WB (18)
ELISA (11)
IF (2)
Peptide-ELISA (1)
rabbit (21)
IgG (14)
polyclonal pc (21)
96-Well Strip Plate (4)
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (9)
aa190-217 (8)
aa179-228 (4)
aa215-249 (1)
aa261-295 (1)
No (31)
Plasma (2)
Serum (2)
Tissue Homogenates (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
PCGF6 Antibody - PCGF6 Antibody western blot of NCI-H292,rat liver,stomach and testis cell line lysates (35 ug/lane). The PCGF6 antibody detected the PCGF6 protein (arrow).
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PCGF6 Rabbit anti-Human Polyclonal (aa190-217) Antibody
Human
WB
Unconjugated
400 µl/$381
PCGF6 Antibody - Immunofluorescence analysis of HeLa cells.
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PCGF6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
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PCGF6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$280; 120 µl/$343; 200 µl/$451
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PCGF6 Rabbit anti-Human Polyclonal (aa190-217) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$653
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PCGF6 Rabbit anti-Human Polyclonal (aa190-217) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$828
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PCGF6 Rabbit anti-Human Polyclonal (aa190-217) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$828
Select
PCGF6 Rabbit anti-Human Polyclonal (aa190-217) (AP) Antibody
Human
ELISA, WB
AP Conjugated
200 µl/$828
Select
PCGF6 Rabbit anti-Human Polyclonal (aa190-217) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$828
Select
PCGF6 Rabbit anti-Human Polyclonal (aa190-217) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$828
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PCGF6 Rabbit anti-Human Polyclonal (aa190-217) (Azide-free) (HRP) Antibody
Human
WB
HRP Conjugated, Azide-free
200 µl/$828
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PCGF6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
PCGF6 Antibody - Western Blot Positive WB detected in: PC3 whole cell lysate, MCF-7 whole cell lysate All Lanes: PCGF6 antibody at 3.1µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 40, 31 KDa Observed band size: 40 KDa
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PCGF6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$284; 100 µg/$348
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PCGF6 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$284; 100 µg/$348
Select
PCGF6 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$284; 100 µg/$348
Select
PCGF6 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$284; 100 µg/$348
PCGF6 Antibody - Anti-PCGF6 Antibody at 1:2000 dilution + rat testis lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 39 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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PCGF6 Rabbit anti-Human Polyclonal (aa215-249) Antibody
Rat
Peptide-ELISA, WB
Unconjugated
400 µl/$376
PCGF6 Antibody - Western blot of lysate from human kidney tissue with PCGF6 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20 ug.
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PCGF6 Rabbit anti-Human Polyclonal (aa261-295) Antibody
Human
WB
Unconjugated
400 µl/$381
PCGF6 Antibody - PCGF6 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PCGF6 Rabbit anti-Human Polyclonal (aa179-228) Antibody
Human, Monkey
WB
Unconjugated
100 µl/$414
PCGF6 Antibody - PCGF6 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PCGF6 Rabbit anti-Human Polyclonal (aa179-228) (HRP) Antibody
Human, Monkey
WB
HRP Conjugated
100 µl/$459
PCGF6 Antibody - PCGF6 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PCGF6 Rabbit anti-Human Polyclonal (aa179-228) (Biotin) Antibody
Human, Monkey
WB
Biotin Conjugated
100 µl/$459
PCGF6 Antibody - PCGF6 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PCGF6 Rabbit anti-Human Polyclonal (aa179-228) (FITC) Antibody
Human, Monkey
WB
FITC Conjugated
100 µl/$459
PCGF6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$746
PCGF6 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$746
PCGF6 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$746
PCGF6 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$744
Viewing 1-25 of 31 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).