ULBP2 / RAET1H

UL16 binding protein 2

Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.

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Products

ELISA Kits (6)

Type

Sandwich (6)

Target

ULBP2 / RAET1H (6)

Reactivity

Human (6)

Format

96-Well Microplate (1)

96-Well Strip Plate (5)

Publications

No (6)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (1)

Plasma (6)

Serum (6)

Tissue Homogenates (2)

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Human ULBP2 / RAET1H (Sandwich ELISA) ELISA Kit - LS-F50056

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

13 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$616

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Human ULBP2 / RAET1H (Sandwich ELISA) ELISA Kit - LS-F12119

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

12.5 - 800 U/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human ULBP2 / RAET1H (Sandwich ELISA) ELISA Kit - LS-F27302

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Human ULBP2 / RAET1H (Sandwich ELISA) ELISA Kit - LS-F35928

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

12.5 - 800 IU/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human ULBP2 / RAET1H (Sandwich ELISA) ELISA Kit - LS-F39931

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$795

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Human ULBP2 / RAET1H (Sandwich ELISA) ELISA Kit - LS-F7483

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$902

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