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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
Protein Family And Group
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IPO13 / LGL2

importin 13

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13.

Gene Name: importin 13
Synonyms: IPO13, IMP13, Importin-13, Karyopherin 13, Late gestation lung 2, KIAA0724, Ran binding protein 13, Ran-binding protein 13, Importin 13, KAP13, Karyopherin-13, LGL2, RANBP13
Target Sequences: NM_014652 NP_055467.3 O94829

☰ Filters
IgG (7)
No (8)
Viewing 1-8 of 8 items
IPO13 / LGL2 Antibody - IHC of paraffin-embedded CL1-5 xenograft using Importin 13 antibody at 1:100 dilution.
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Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Mouse, Bovine, Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100µl   1.02mg/ml   $355.00
Select
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $335.00
IPO13 / LGL2 Antibody
Select
Rabbit Polyclonal to Human IPO13 / LGL2
Human
ELISA, IHC, WB
Unconjugated
100µg   1mg/ml   $265.00
IPO13 / LGL2 Antibody - Western blot analysis of extracts of HeLa cells using IPO13 antibody. The lane on the left was treated with blocking peptide.
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Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
IPO13 / LGL2 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue using IPO13 Antibody at dilution of 1:100
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Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA
Unconjugated
50µg   $285.00; 100µg   $385.00
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Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human IPO13 / LGL2
Human
ELISA
FITC Conjugated
50µg   $285.00; 100µg   $385.00

Viewing 1-8 of 8 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).