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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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HHV-8 ORF8

KSHV (HHV-8) ORF8

KSHV (Human Herpesvirus 8) is a herpesvirus, and is a large double-stranded DNA virus with a protein covering that packages its nucleic acids, called the capsid, which is then surrounded by an amorphous protein layer called the tegument, and finally enclosed in a lipid envelope derived in part from the cell membrane. KSHV has a genome which is approximately 165,000 nucleic acid bases in length. It is a rhadinovirus, and is remarkable since it has stolen numerous genes from host cells including genes that encode for complement-binding protein, IL-6, BCL-2, cyclin-D, a G protein-coupled receptor, interferon regulatory factor and Flice inhibitory protein (FLIP), as well as DNA synthesis proteins including dihydrofolate reductase, thymidine kinase, thymidylate synthetase, DNA polymerase and many others. While no other human tumor virus possesses these same genes, other tumor viruses target the same cellular pathways illustrating that at a basic level, all tumor viruses appear to attack the same cellular control pathways, so-called tumor suppressor pathways.[citation needed]

HHV-8 ORF8 Target Details

Target Name: KSHV (HHV-8) ORF8

☰ Filters
Antibodies (2)
Primary (2)
HHV-8 ORF8 (2)
Human (1)
Human Herpesvirus 8 (1)
WB (2)
ELISA (1)
rabbit (2)
polyclonal pc (2)
Unconjugated (2)
No (2)
Select
HHV-8 ORF8 Rabbit anti-Human Herpesvirus 8 Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$465
HHV-8 ORF8 Antibody
Select
HHV-8 ORF8 Rabbit anti-Human Herpesvirus 8 Polyclonal Antibody
Human Herpesvirus 8
WB
Unconjugated
100 µg/$315
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).