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TAPBP / Tapasin

TAP binding protein (tapasin)

TAPBP / Tapasin is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Gene Name: TAP binding protein (tapasin)
Synonyms: TAPBP, TAP binding protein (tapasin), TAPA, TAP-associated protein, TAP-binding protein, TPN, NGS17, NGS-17, Tapasin, TPSN
Target Sequences: NM_003190 NP_003181.3 O15533

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Products
Proteins (10)
Over-Expression Lysate (6)
Recombinant (4)
TAPBP / Tapasin (10)
SDS-PAGE (1)
No (10)
GST, N-terminus (1)
His (1)
His,C-terminus (1)
Myc-DDK (Flag) (7)
Human (7)
293T Cells (3)
HEK 293 Cells (5)
Human Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
TAPBP / Tapasin Protein
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HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human TAPBP consists 405 amino acids and predicts a molecular mass of 43.5 kDa.
100 µg/$480
TAPBP / Tapasin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TAPBP / Tapasin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
47.63 kDa
20 µg/$215
TAPBP / Tapasin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36.3 kDa
20 µg/$150
TAPBP / Tapasin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51.9 kDa
20 µg/$150
TAPBP / Tapasin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36.3 kDa
100 µg/$494
TAPBP / Tapasin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51.9 kDa
100 µg/$494
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
43.5 kDa
100 µg/$843
TAPBP / Tapasin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
47.63 kDa
100 µg/$710
TAPBP / Tapasin Protein - Purified recombinant protein TAPBP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.6 kDa
20 µg/$1,107
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).