TAF4

TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and vitamin D3 receptors. In addition, this subunit interacts with the transcription factor CREB, which has a glutamine-rich activation domain, and binds to other proteins containing glutamine-rich regions. Aberrant binding to this subunit by proteins with expanded polyglutamine regions has been suggested as one of the pathogenetic mechanisms underlying a group of neurodegenerative disorders referred to as polyglutamine diseases.

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Antibodies (11)

ELISA Kits (2)

Proteins (1)

Type

Cell-Based (1)

Primary (11)

Recombinant (1)

Sandwich (1)

Target

TAF4 (14)

Reactivity

Human (11)

Mouse (8)

Rat (4)

Bat (3)

Bovine (3)

Chicken (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (3)

Pig (3)

Rabbit (3)

Xenopus (3)

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Application

IHC (1)

IHC-P (1)

WB (11)

Flo (1)

ELISA (2)

IF (1)

Peptide-ELISA (2)

Host

rabbit (10)

mouse (1)

Isotype

Ig (1)

IgG (3)

IgG1 (1)

Clonality

monoclonal mc (1)

polyclonal pc (10)

Format

96-Well Microplate (1)

96-Well Strip Plate (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (8)

Epitope

aa935-984 (4)

C-Terminus (2)

Glu977 (1)

Publications

No (14)

Sample Type

Adherent Cell Cultures (1)

Plasma (1)

Serum (1)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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TAF4 Antibody (C-Terminus) LS-C757660

Antibody:

TAF4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$393

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TAF4 Antibody LS-C800421

Antibody:

TAF4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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TAF4 Antibody (Glu977) LS-C192005

Antibody:

TAF4 Rabbit anti-Human Polyclonal (Glu977) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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TAF4 Antibody LS-C822420

Antibody:

TAF4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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TAF4 Antibody (C-Terminus) LS-C118650

Antibody:

TAF4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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TAF4 Antibody LS-C76196

Antibody:

TAF4 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

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TAF4 Antibody (aa935-984) LS-C109786

Antibody:

TAF4 Rabbit anti-Human Polyclonal (aa935-984) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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TAF4 Antibody (aa935-984, HRP) LS-C429483

Antibody:

TAF4 Rabbit anti-Human Polyclonal (aa935-984) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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TAF4 Antibody (aa935-984, Biotin) LS-C429482

Antibody:

TAF4 Rabbit anti-Human Polyclonal (aa935-984) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

TAF4 Antibody (aa935-984, FITC) LS-C429481

Antibody:

TAF4 Rabbit anti-Human Polyclonal (aa935-984) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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TAF4 Antibody LS-C415999

Antibody:

TAF4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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Human TAF4 Protein (Recombinant GST, N-terminus) (aa715-800) - LS-G60271

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse TAF4 (Sandwich ELISA) ELISA Kit - LS-F38443

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse/Human TAF4 (Cell-Based ELISA) ELISA Kit - LS-F2994

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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