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TAF11

TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
Synonyms: TAF11, TAFII28, TAF(II)28, PRO2134, MGC:15243, TAF2I, TAFII-28, TFIID subunit p30-beta
Target Sequences: NM_005643 NP_005634.1 Q15544

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
TAF11 (6)
No (6)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
TAF11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.1 kDa
100 µg/$494
TAF11 Protein - 12.5% SDS-PAGE of human TAF11 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.7 kDa
10 µg/$479; 25 µg/$670
TAF11 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
TAF11 Protein - Purified recombinant protein TAF11 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.1 kDa
20 µg/$1,107
TAF11 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TAF11 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.1 kDa
20 µg/$150
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).