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TAC1

tachykinin, precursor 1

TAC1 / Substance P is four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: tachykinin, precursor 1
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: TAC1, Hs.2563, Neurokinin 1, Neurokinin 2, Neuromedin L, Neuropeptide K, NK2, NPK, Protachykinin beta, Protachykinin-1, Substance K, Substance P, Tachykinin, precursor 1, Neurokinin A, Neuropeptide gamma, PPT, Neurokinin alpha, NKA, NKNA, TAC2, Tachykinin 2
Target Sequences: NM_003182 NP_003173.1 P20366

Publications (3)

1
Characterization of Autonomic Nerve Markers and Lymphocyte Subsets in the Ileal Peyer’s Patch of Pigs Infected Experimentally with Brachyspira hyodysenteriae. J. Kaleczyc, P. Podlasz, A. Winnick, W. Wasowicz, W. Sienkiewicz, J. Zmudzki and M. Lakomy. Journal of comparative pathology. 2010 143:248-57. (IHC-Fr; Pig) [Full Text Article] [PubMed:20605161]
2
Up-regulated expression of substance P in CD8(+) T cells and NK1R on monocytes of atopic dermatitis. Zhang Z, Zheng W, Xie H, Chai R, Wang J, Zhang H, He S. Journal of translational medicine. 2017 15:93. (IHC; Human) [Full Text Article] [PubMed:28460633] [PMC:PMC5412038] Related Antibodies: LS-C539494.
3
Neuropeptides and lymphocyte populations in the porcine ileum and ileocecal lymph nodes during postnatal life. Krzysztof Wasowicz, Anna Winnicka, Jerzy Kaleczyc, Michal Zalecki, Piotr Podlasz, Zenon Pidsudko. PloS one. 2018 May;13:e0196458. [Full Text Article] [PubMed:29813072] [PMC:PMC5973590]

☰ Filters
Antibodies (75)
ELISA Kits (23)
Proteins (8)
Competitive EIA (14)
Custom (2)
Over-Expression Lysate (2)
Primary (75)
Recombinant (5)
Sandwich (7)
Synthetic Peptide (1)
TAC1 (106)
Human (72)
Mouse (20)
Rat (30)
Bat (1)
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Cow (1)
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Fish (1)
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Hamster (1)
Horse (4)
Monkey (1)
Pig (5)
Rabbit (6)
Sheep (1)
IHC (35)
IHC-Fr (11)
IHC-P (13)
WB (20)
Flo (8)
ELISA (33)
ICC (1)
IF (10)
Peptide-ELISA (1)
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rabbit (54)
mouse (9)
chicken (2)
guinea pig (6)
rat (4)
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monoclonal mc (13)
polyclonal pc (62)
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aa102-129 (8)
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TAC1  Antibody - Immunohistochemistry of paraffin-embedded human small intestine using antibody 1:100 dilution.
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TAC1 Rabbit anti-Human Polyclonal (aa1-129) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$282; 100 µl/$348
Select
TAC1 Rabbit anti-Human Polyclonal (aa102-129) (FITC) Antibody
Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$825
TAC1  ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$772
TAC1  ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
4.69 - 300 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$744
TAC1  ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$746
Select
TAC1 Rat Monoclonal (C-Terminus) (Supernatant) (NC1/34) Antibody
Bovine
IF, IHC, IHC-Fr, IHC-P
Unconjugated, Supernatant
0.1 ml/$471
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TAC1 Mouse anti-Human Monoclonal (FITC) Antibody
Rat, Human
ELISA, IHC
FITC Conjugated
100 µl/$984
Select
TAC1 Guinea pig Polyclonal Antibody
Rat
IF, IHC, IHC-Fr
Unconjugated
50 µl/$852
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TAC1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µg/$231; 100 µg/$293; 200 µg/$324; 500 µg/$442
TAC1  Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TAC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
TAC1  ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Guinea pig
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
TAC1  ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$557
TAC1  Antibody - Anti-TAC1 / Substance P antibody IHC staining of human small intestine, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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TAC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, RIA
Unconjugated
50 µl/$485
Select
TAC1 Guinea pig anti-Human Polyclonal Antibody
Rabbit, Rat, Human
IF, IHC, IHC-Fr
Unconjugated
50 µl/$734
Select
TAC1 Mouse anti-Human Monoclonal (SP-DE4-21) Antibody
Chicken, Human
ELISA, IHC
Unconjugated
10 µg/$414; 100 µg/$728
TAC1  Antibody - Western blot of extracts of 293 cell lines, using TAC1 antibody.
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TAC1 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$433
TAC1  Antibody - Western blot analysis of lysates from human whole brain tissue, using Tachykinin antibody.
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TAC1 Rabbit anti-Human Polyclonal (aa54-103) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$318; 100 µl/$378
TAC1  Antibody - Western blot analysis of Protachykinin 1 expression in HEK293T (A); SP2/0 (B); H9C2 (C) whole cell lysates.
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TAC1 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Rat, Human
WB
Unconjugated
100 µl/$289
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TAC1 Guinea pig anti-Rat Polyclonal (aa1-11) Antibody
Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Horse, Bat, Human, Monkey
IF
Unconjugated
50 µl/$461
Select
TAC1 Guinea pig anti-Rat Polyclonal (aa1-11) Antibody
Mouse, Rat, Human
IHC
Unconjugated
50 µl/$474
Select
TAC1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
100 µl/$307; 200 µl/$355; 500 µl/$509; 1 ml/$594
Select
TAC1 Rat anti-Human Monoclonal Antibody
Human
IF, IHC, IHC-Fr, IHC-P
Unconjugated
100 µl/$710
Select
TAC1 Rabbit anti-Human Polyclonal Antibody
Chicken, Human
IF, IHC, IHC-Fr, IHC-P
Unconjugated
500 µl/$541
TAC1  ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$809
TAC1  ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
123.5 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$821
Viewing 1-25 of 106 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).