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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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TAB1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

TAB1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1
Synonyms: TAB1, 3'-Tab1, 3-Tab1, MAP3K7IP1, TAK1-binding protein 1
Target Sequences: NM_006116 NP_006107.1 Q15750


TAB1 Antibody - Anti-TAB1 / MAP3K7IP1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
Select
Rabbit Monoclonal (IgG) to Human TAB1
Human, Monkey
IP, WB
Unconjugated
100µl   $530.00
TAB1 Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Select
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $285.00; 100µl   $385.00
TAB1 Antibody - Western blot analysis of extracts of various cells.
Select
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
IF, IHC, WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $315.00; 200µl   $425.00
TAB1 Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal to Human TAB1
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl   1mg/ml   $385.00
TAB1 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using TAB1 Polyclonal Antibody at dilution of 1:40.
Select
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, IHC
Unconjugated
20µl   0.2mg/ml   $205.00; 60µl   0.2mg/ml   $235.00; 120µl   0.2mg/ml   $295.00; 200µl   0.2mg/ml   $395.00
TAB1 Antibody
Select
Mouse Monoclonal (IgG2a,k) to Human TAB1
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl   $305.00
TAB1 Antibody - Western blot detection of TAB1 (N-term) in K562 and Hela lysates using TAB1 (N-term) mouse mAb (1:1000 diluted). Predicted band size: 55KDa. Observed band size: 55KDa.
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Mouse Monoclonal to Human TAB1
Human
ELISA, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Goat Polyclonal (IgG) to Human TAB1
Mouse, Human
ICC, WB
Unconjugated
100µg   $770.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
PE Conjugated
200µl   $740.00
TAB1 Antibody - Western blot analysis of TAB1 expression in MCF-7 cells lysate. The lane on the left is treated with the antigen-specific peptide.
Select
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
DB, ELISA
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
IP, WB
Unconjugated
100µl   0.2mg/ml   $405.00
Select
Rabbit Polyclonal (IgG) to Human TAB1
Human
IP, WB
Unconjugated
100µl   1mg/ml   $405.00
Viewing 1-25 of 59 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).