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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TAB1

TGF-beta activated kinase 1/MAP3K7 binding protein 1

TAB1 was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Gene Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1
Synonyms: TAB1, 3'-Tab1, 3-Tab1, MAP3K7IP1, TAK1-binding protein 1
Target Sequences: NM_006116 NP_006107.1 Q15750

Filtered by: None
Target
TAB1 (58)
Reactivity
Human (58)
Mouse (21)
Rat (12)
Bat (1)
Bovine (2)
Chicken (4)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (1)
Horse (1)
Monkey (6)
Pig (6)
Rabbit (5)
Sheep (1)
Application
IHC (8)
IHC-P (2)
WB (49)
DB (7)
ELISA (29)
ICC (2)
IF (2)
IP (3)
Host
rabbit (53)
mouse (4)
goat (1)
Isotype
IgG (34)
IgG2a,k (1)
Clonality
monoclonal mc (5)
polyclonal pc (53)
Format
AP Conjugated (3)
APC (1)
APC Conjugated (4)
Azide-free (3)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (30)
Epitope
aa189-439 (8)
aa401-430 (8)
aa416-445 (8)
pSer423 (7)
N-Terminus (5)
C-Terminus (1)
Pro381 (1)
aa205-504 (1)
aa304-321 (1)
aa435-485 (1)
aa485-504 (1)
aa7-159 (1)
aa78-108 (1)
Publications
No (58)
Showing 1-25 of 58 results

IHC-plus™ TAB1 Antibody LS-B584
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-TAB1 / MAP3K7IP1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of TAB1 in 3T3 cells with TAB1 antibody at 2 ug/ml.

TAB1 Antibody (Pro381) LS-C39459
Rabbit Monoclonal (IgG) to Human TAB1
Human, Monkey
IP, WB
Unconjugated
100µl  $530.00

TAB1 Antibody (aa205-504) LS-C377604
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human rectum using antibody at 1:100 dilution.

TAB1 Antibody LS-C334263
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
IF, IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Western blot analysis of extracts of various cells.

TAB1 Antibody LS-C401826
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, IHC, WB
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human colon cancer using TAB1 Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Human brain using TAB1 Polyclonal Antibody at dilution of 1:50.

TAB1 Antibody LS-C806711
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

TAB1 Antibody LS-C771022
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, IHC
Unconjugated
20µl 0.5mg/ml  $205.00; 60µl 0.5mg/ml  $235.00; 120µl 0.5mg/ml  $295.00; 200µl 0.5mg/ml  $395.00

TAB1 Antibody LS-C341320
Rabbit Polyclonal to Human TAB1
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl 1mg/ml  $385.00

TAB1 Antibody LS-C405134
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, IHC
Unconjugated
20µl 0.4mg/ml  $205.00; 60µl 0.4mg/ml  $235.00; 120µl 0.4mg/ml  $295.00; 200µl 0.4mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human thyroid cancer using TAB1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of paraffin-embedded Human thyroid cancer using TAB1 Polyclonal Antibody at dilution of 1:40.

TAB1 Antibody LS-C62050
Mouse Monoclonal (IgG2a,k) to Human TAB1
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl  $305.00
Western blot Image

TAB1 Antibody (aa7-159) LS-C39460
Goat Polyclonal (IgG) to Human TAB1
Mouse, Human
ICC, WB
Unconjugated
100µg  $770.00

TAB1 Antibody (aa401-430) LS-C328834
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
Unconjugated
200µl  $590.00

TAB1 Antibody (aa401-430, Biotin) LS-C283340
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

TAB1 Antibody (aa401-430, FITC) LS-C283339
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

TAB1 Antibody (aa401-430, AP) LS-C283337
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
AP Conjugated
200µl  $740.00

TAB1 Antibody (aa401-430, APC) LS-C283338
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
APC Conjugated
200µl  $740.00

TAB1 Antibody (aa401-430, PE) LS-C283341
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
PE Conjugated
200µl  $740.00

TAB1 Antibody (aa401-430, Azide-free, HRP) LS-C283342
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

TAB1 Antibody (aa416-445) LS-C328835
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
Unconjugated
200µl  $590.00

TAB1 Antibody (aa416-445, Biotin) LS-C283345
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

TAB1 Antibody (aa416-445, APC) LS-C283343
Rabbit Polyclonal (IgG) to Human TAB1
Human
ELISA, WB
APC Conjugated
200µl  $740.00

TAB1 Antibody LS-C804041
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image

TAB1 Antibody (phospho-Ser423) LS-C328831
Rabbit Polyclonal (IgG) to Human TAB1
Human
DB, ELISA
Unconjugated
200µl  $590.00

TAB1 Antibody (aa435-485) LS-C288920
Rabbit Polyclonal (IgG) to Human TAB1
Mouse, Human
IP, WB
Unconjugated
100µl 0.2mg/ml  $395.00

TAB1 Antibody (aa485-504) LS-C288921
Rabbit Polyclonal (IgG) to Human TAB1
Human
IP, WB
Unconjugated
100µl 1mg/ml  $395.00
Showing 1-25 of 58 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).