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SYTL2 / SLP2

Synaptotagmin-Like 2

Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca2+ while binding to PIP2 is Ca2+ insensitive.

Gene Name: Synaptotagmin-Like 2
Synonyms: SYTL2, CHR11SYT, EXO4, Exophilin-4, KIAA1597, SGA72M, SLP2, Synaptotagmin-like protein 2, Synaptotagmin-like 2, SLP2A, Chromosome 11 synaptotagmin
Target Sequences: NM_032943 NP_116561.1 Q9HCH5

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SYTL2 / SLP2 (1)
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SYTL2 / SLP2 ELISA Kit
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0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).