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SYNE1 / Nesprin 1

spectrin repeat containing, nuclear envelope 1

Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. May be involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. May be required for centrosome migration to the apical cell surface during early ciliogenesis.

Gene Name: spectrin repeat containing, nuclear envelope 1
Synonyms: SYNE1, 8B, ARCA1, C6orf98, CPG2, DJ45H2.2, EDMD4, Enaptin, KIAA0796, MYNE1, Nesp1, KIAA1262, KIAA1756, Syne-1, Myne-1, SCAR8, SYNE-1B, Nesprin 1, Nesprin-1
Target Sequences: AY061755 AAL33798.1 Q8NF91

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Proteins (2)
Recombinant (2)
SYNE1 / Nesprin 1 (2)
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GST, N-terminus (1)
His-T7 (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
SYNE1 / Nesprin 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SYNE1 / Nesprin 1 Protein - Recombinant Nesprin 1 By SDS-PAGE
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E. coli
His-T7
32.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).