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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SYNCRIP / HnRNP Q

synaptotagmin binding, cytoplasmic RNA interacting protein

Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation; seems not to be essential for GAIT complex function.

Gene Name: synaptotagmin binding, cytoplasmic RNA interacting protein
Synonyms: SYNCRIP, DJ3J17.2, GRYRBP, HnRNP-Q, HNRPQ, HNRPQ1, HnRNP Q, NS1-associated protein 1, NSAP1, GRY-RBP, PP68
Target Sequences: NM_006372 NP_006363.4 O60506

Publications (1)

1
Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing. Wongpalee SP, Vashisht A, Sharma S, Chui D, Wohlschlegel JA, Black DL. eLife. 2016 5: (WB; Human) [Full Text Article] [PubMed:27882870] [PMC:PMC5122456] Related Antibodies: LS-C31342.

Filtered By: None
Target
SYNCRIP / HnRNP Q (25)
Reactivity
Human (25)
Mouse (19)
Rat (17)
Bat (8)
Bovine (9)
Chicken (4)
Chimpanzee (6)
Dog (9)
Gibbon (6)
Guinea pig (8)
Hamster (8)
Horse (8)
Monkey (8)
Pig (9)
Rabbit (9)
Xenopus (6)
Zebrafish (5)
Application
IHC (11)
IHC-P (6)
WB (25)
ELISA (8)
ICC (1)
IF (9)
IP (3)
Peptide-ELISA (2)
Host
rabbit (23)
mouse (2)
Isotype
IgG (17)
IgG1 (2)
Clonality
monoclonal mc (2)
polyclonal pc (23)
Clone
I8E4 (2)
Format
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (16)
Epitope
N-Terminus (4)
aa401-450 (4)
210-290 aa, Internal (1)
Glu268 (1)
Internal (1)
aa219-268 (1)
aa236-285 (1)
aa591-623 (1)
Publications
No (24)
Yes (1)
Showing 1-25 of 25 results

SYNCRIP / HnRNP Q Antibody (aa236-285) IHC-plus™ LS-B9133
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Human, Brain, neurons: Formalin-Fixed Paraffin-Embedded (FFPE)
Immunofluorescence analysis of HepG2 cells, using hnRNP Q Antibody. The picture on the right is blocked with the synthesized peptide.
Human, Brain, neurons: Formalin-Fixed Paraffin-Embedded (FFPE)
Immunofluorescence analysis of HepG2 cells, using hnRNP Q Antibody. The picture on the right is blocked with the synthesized peptide.

SYNCRIP / HnRNP Q Antibody (N-Terminus) LS-C31342
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100µg  $325.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (N-Terminus, HRP) LS-C440806
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $335.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (N-Terminus, Biotin) LS-C440805
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $335.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (N-Terminus, FITC) LS-C440807
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $335.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody IHC-plus™ LS-B11374
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Human
ELISA IHC IHC-P WB
Unconjugated
100µg  $565.00
Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (HRP) LS-C211698
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Human
ELISA IHC IHC-P WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00
Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (Biotin) LS-C211701
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Human
ELISA IHC IHC-P WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00
Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (FITC) LS-C211703
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Human
ELISA IHC IHC-P WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00
Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-SYNCRIP / HnRNP Q antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody LS-C755260
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Human
ELISA IF IHC WB
Unconjugated
100µg  $355.00

SYNCRIP / HnRNP Q Antibody (210-290 aa, Internal) LS-C383992
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated
100µl 1mg/ml  $265.00
Western blot of hnRNP Q antibody
Western blot of hnRNP Q antibody
Western blot of hnRNP Q antibody
Western blot of hnRNP Q antibody

SYNCRIP / HnRNP Q Antibody LS-C346291
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Mouse, Rat, Human
IF IHC WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human liver cancer tissue.
Immunohistochemistry of paraffin-embedded mouse kidney tissue.
Immunohistochemistry of paraffin-embedded human liver cancer tissue.
Immunohistochemistry of paraffin-embedded mouse kidney tissue.

SYNCRIP / HnRNP Q Antibody (clone I8E4) LS-C82266
Mouse Monoclonal [clone I8E4] (IgG1) to Human SYNCRIP / HnRNP Q
Xenopus, Mouse, Human
ELISA IF IP WB
Unconjugated
50µl  $380.00

SYNCRIP / HnRNP Q Antibody (clone I8E4) LS-C82224
Mouse Monoclonal [clone I8E4] (IgG1) to Human SYNCRIP / HnRNP Q
Xenopus, Mouse, Human
ELISA IF IP WB
Unconjugated
100µl  $450.00
Western blot of Anti-hnRNP-Q, clone I8E4 on HeLa cell lysate
Western blot of Anti-hnRNP-Q, clone I8E4 on HeLa cell lysate

SYNCRIP / HnRNP Q Antibody (Internal) LS-C353261
Rabbit Polyclonal to Human SYNCRIP / HnRNP Q
Zebrafish, Pig, Rat, Rabbit, Mouse, Dog, Bovine, Human
ICC IF IP WB
Unconjugated
100µl 1mg/ml  $245.00
Immunofluorescent analysis of hnRNP Q staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Western blot analysis of hnRNP Q expression in HT1080 (A); HeLa (B); HUVEC (C) whole cell lysates.
Immunofluorescent analysis of hnRNP Q staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Western blot analysis of hnRNP Q expression in HT1080 (A); HeLa (B); HUVEC (C) whole cell lysates.

SYNCRIP / HnRNP Q Antibody LS-C412799
Rabbit Polyclonal to Human SYNCRIP / HnRNP Q
Mouse, Rat, Human
IF IHC WB
Unconjugated
100µl  $385.00

SYNCRIP / HnRNP Q Antibody (aa591-623) LS-C97166
Rabbit Polyclonal to Human SYNCRIP / HnRNP Q
Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human brain tissue reacted with HNRPQ antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of HNRPQ Antibody in HeLa and Jurkat cell line lysates (35 ug/lane). HNRPQ (arrow) was detected using the purified antibody.
Formalin-fixed and paraffin-embedded human brain tissue reacted with HNRPQ antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of HNRPQ Antibody in HeLa and Jurkat cell line lysates (35 ug/lane). HNRPQ (arrow) was detected using the purified antibody.

SYNCRIP / HnRNP Q Antibody LS-C658770
Rabbit Polyclonal to Human SYNCRIP / HnRNP Q
Mouse, Rat, Human
IF WB
Unconjugated
100µl  $305.00

SYNCRIP / HnRNP Q Antibody (Glu268) LS-C191924
Rabbit Polyclonal to Human SYNCRIP / HnRNP Q
Mouse, Rat, Human
IHC WB
Unconjugated
100µl  $345.00

SYNCRIP / HnRNP Q Antibody (aa219-268) LS-C292064
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Mouse, Rat, Human
Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of the lysates from HT-29 cells using hnRNP Q antibody.
Western blot analysis of the lysates from HT-29 cells using hnRNP Q antibody.

SYNCRIP / HnRNP Q Antibody LS-C417050
Rabbit Polyclonal to Human SYNCRIP / HnRNP Q
Mouse, Rat, Human
WB
Unconjugated
100µg 1mg/ml  $305.00

SYNCRIP / HnRNP Q Antibody (aa401-450) LS-C31953
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Bat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
100µg  $325.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (aa401-450, HRP) LS-C440810
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $335.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (aa401-450, Biotin) LS-C440808
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $335.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

SYNCRIP / HnRNP Q Antibody (aa401-450, FITC) LS-C440809
Rabbit Polyclonal (IgG) to Human SYNCRIP / HnRNP Q
Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $335.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 25 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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