SYNCAM / CADM1

cell adhesion molecule 1

Mediates homophilic cell-cell adhesion in a Ca2+-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly By similarity. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

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Products

Proteins (13)

Type

Over-Expression Lysate (4)

Recombinant (9)

Target

SYNCAM / CADM1 (13)

Publications

No (13)

Tag

Fc, C-terminus (2)

GST, N-terminus (1)

His (2)

His,C-terminus (2)

His-GST (1)

Myc-DDK (Flag) (5)

Species

Human (7)

Mouse (4)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (4)

Human Cells (2)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (5)

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Human SYNCAM / CADM1 Protein (Recombinant His,C-terminus) (Met1-His374) - LS-G138037

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.5 kDa

Price:

100 µg/$721

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Human SYNCAM / CADM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86239

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.4 kDa

Price:

20 µg/$150

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Human SYNCAM / CADM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86240

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.3 kDa

Price:

20 µg/$215

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Mouse SYNCAM / CADM1 Protein (Recombinant Fc, C-terminus) (Gln48-His388) - LS-G139299

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

65.3 kDa

Price:

10 µg/$281; 50 µg/$389

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SYNCAM / CADM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119243

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.4 kDa

Price:

100 µg/$494

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Human SYNCAM / CADM1 Protein (Recombinant His) - LS-G3055

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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Human SYNCAM / CADM1 Protein (Recombinant His-GST) (aa27-292) - LS-G25475

Source:

E. coli

Tag:

His-GST

Molecular Weight:

60.0 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human SYNCAM / CADM1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70083

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.3 kDa

Price:

20 µg/$1,107

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Human SYNCAM / CADM1 Protein (Recombinant GST, N-terminus) (aa151-250) - LS-G62065

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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SYNCAM / CADM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101200

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.3 kDa

Price:

100 µg/$710

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Mouse SYNCAM / CADM1 Protein (Recombinant His,C-terminus) (Gln48-His388) - LS-G139389

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

39.2 kDa

Price:

10 µg/$281; 50 µg/$389

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Mouse SYNCAM / CADM1 Protein (Recombinant Fc, C-terminus) (Gln48-His388) - LS-G39160

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

65.3kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Mouse SYNCAM / CADM1 Protein (Recombinant His) (Met1-His377) - LS-G98067

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

38.5 kDa

Price:

50 µg/$483

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