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SYN1 / Synapsin 1

synapsin I

SYN1 / Synapsin 1 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: synapsin I
Family/Subfamily: Synapsin
Synonyms: SYN1, Brain protein 4.1, Synapsin, Synapsin I, Synapsin-1, SYN1a, SYN1b, SYNI
Target Sequences: NM_006950 NP_008881.2 P17600

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Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
SYN1 / Synapsin 1 (9)
No (9)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (5)
Human (6)
Mouse (1)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Yeast (1)
SYN1 / Synapsin 1 Protein - Recombinant Synapsin I By SDS-PAGE
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E. coli
6His, N-terminus
38.3 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
SYN1 / Synapsin 1 Protein
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Yeast
His
36.6 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
SYN1 / Synapsin 1 Protein - Purified recombinant protein SYN1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
73.9 kDa
20 µg/$1,107
SYN1 / Synapsin 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
GST
62 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
SYN1 / Synapsin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
69.9 kDa
100 µg/$710
SYN1 / Synapsin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
73.9 kDa
20 µg/$215
SYN1 / Synapsin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
69.9 kDa
20 µg/$215
SYN1 / Synapsin 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
73.9 kDa
100 µg/$710
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).