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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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We could not find product '(ID:552806)'. Here are some alternate products to this target that might be of interest to you.



SUMO1 / SMT3

small ubiquitin-like modifier 1

Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.

Gene Name: small ubiquitin-like modifier 1
Synonyms: SUMO1, GAP modifying protein 1, GMP1, OFC10, Sentrin, SMT3 homolog 3, SMT3C, SMT3H3, SUMO-1, Ubiquitin-like protein UBL1, PIC1, Ubiquitin-like 1 (sentrin), UBL1, DAP1, GAP-modifying protein 1, Ubiquitin-like protein SMT3C
Target Sequences: NM_003352 NP_003343.1 P63165

Publications (4)

1
SUMO modification of the Ets-related transcription factor ERM inhibits its transcriptional activity. Degerny C, Monte D, Beaudoin C, Jaffray E, Portois L, Hay RT, de Launoit Y, Baert JL. The Journal of biological chemistry. 2005 280:24330-8. [PubMed:15857832] Related Antibodies: LS-C161612.
2
SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7. Janer A, Werner A, Takahashi-Fujigasaki J, Daret A, Fujigasaki H, Takada K, Duyckaerts C, Brice A, Dejean A, Sittler A. Human molecular genetics. 2010 19:181-95. [PubMed:19843541]
3
Insights into high affinity small ubiquitin-like modifier (SUMO) recognition by SUMO-interacting motifs (SIMs) revealed by a combination of NMR and peptide array analysis. Namanja AT, Li YJ, Su Y, Wong S, Lu J, Colson LT, Wu C, Li SS, Chen Y. The Journal of biological chemistry. 2012 287:3231-40. [PubMed:22147707] [PMC:PMC3270977] Related Antibodies: LS-C96460.
4
Transition from a nucleosome-based to a protamine-based chromatin configuration during spermiogenesis in Drosophila. Rathke C, Baarends WM, Jayaramaiah-Raja S, Bartkuhn M, Renkawitz R, Renkawitz-Pohl R. Journal of cell science. 2007 120:1689-700. [PubMed:17452629] Related Antibodies: LS-C98764.
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Viewing 1-25 of 107 items
SUMO1 / SMT3 Antibody - Anti-SUMO1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
SUMO1 / SMT3 Antibody - Anti-SUMO1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
SUMO1 / SMT3 Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with SUMO1 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
(1) Publication(s)
Rabbit Polyclonal to Human SUMO1 / SMT3
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
SUMO1 / SMT3 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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(1) Publication(s)
Rabbit Polyclonal to Human SUMO1 / SMT3
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
SUMO1 / SMT3 Antibody - The SUMO1 monoclonal antibody is used in Western blot to detect SUMO1 in HL60 cell lysate.
Select
(1) Publication(s)
Mouse Monoclonal [clone 66AT1273.94] (IgG1) to Human SUMO1 / SMT3
Human
WB
Unconjugated
400µl   $325.00
SUMO1 / SMT3 Antibody - Immunohistochemistry of paraffin-embedded mouse placenta using SUMO1 antibodyat dilution of 1:100 (40x lens).
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Rabbit Monoclonal to Human SUMO1 / SMT3
Mouse, Rat, Human
ChIP-Seq, Flo, IF, IHC, IP, WB
Unconjugated
50µl   $295.00; 100µl   $385.00; 200µl   $560.00
Select
Mouse Monoclonal (IgG1,k) to Human SUMO1 / SMT3
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µg   $635.00
SUMO1 / SMT3 Antibody
Select
Mouse Monoclonal [clone 5B12] (IgG1) to Human SUMO1 / SMT3
Mouse, Rat, Human
ICC, WB
Unconjugated
100µg   1mg/ml   $345.00
SUMO1 / SMT3 Antibody - Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with SUMO-1 antibody (SUMO1/1188).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone SUMO1/1188] (IgG1,k) to Human SUMO1 / SMT3
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
SUMO1 / SMT3 Antibody - Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with SUMO-1 antibody (SUMO1/1188).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone SUMO1/1188] (IgG1,k) to Human SUMO1 / SMT3
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
SUMO1 / SMT3 Antibody - Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with SUMO-1 antibody (SUMO1/1188).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone SUMO1/1188] (IgG1,k) to Human SUMO1 / SMT3
Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7ml   $465.00
SUMO1 / SMT3 Antibody - IHC staining of human tonsil with SUMO1 antibody (clone S1MT-2).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone S1MT-2] (IgG1,k) to Human SUMO1 / SMT3
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
SUMO1 / SMT3 Antibody - IHC staining of human tonsil with SUMO1 antibody (clone S1MT-2).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S1MT-2] (IgG1,k) to Human SUMO1 / SMT3
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7ml   $465.00
SUMO1 / SMT3 Antibody - IHC staining of human tonsil with SUMO1 antibody (clone S1MT-2).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S1MT-2] (IgG1,k) to Human SUMO1 / SMT3
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
SUMO1 / SMT3 Antibody
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human SUMO1 / SMT3
Human
ELISA, Flo, ICC, IF, IHC, WB
AP Conjugated
200µl   $740.00
SUMO1 / SMT3 Antibody - SUMO1 antibody SM1/495 immunohistochemistry tonsil.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone SM1/495] (IgG1,k) to Human SUMO1 / SMT3
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
SUMO1 / SMT3 Antibody - SUMO1 antibody SM1/495 immunohistochemistry tonsil.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone SM1/495] (IgG1,k) to Human SUMO1 / SMT3
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7ml   $465.00
SUMO1 / SMT3 Antibody - SUMO1 antibody SM1/495 immunohistochemistry tonsil.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone SM1/495] (IgG1,k) to Human SUMO1 / SMT3
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00

Viewing 1-25 of 107 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).