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SULF2 / Sulfatase 2

sulfatase 2

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).

Gene Name:	sulfatase 2
Synonyms:	SULF2, Extracellular sulfatase Sulf-2, KIAA1247, Sulfatase 2, HSULF-2, SULF-2
Target Sequences:	AB033073 Q8IWU5 Q8IWU5

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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