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STRA13

stimulated by retinoic acid 13

DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays an important role in mitotic progression and chromosome segregation.

Gene Name:	stimulated by retinoic acid 13
Synonyms:	STRA13, CENPX, HLHB2, Stimulated by retinoic acid 13, MHF2, CENP-X, Centromere protein X, FAAP10
Target Sequences:	U95006 NP_659435.2 A8MT69

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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