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STK39 / SPAK

serine threonine kinase 39

STK39 / SPAK is a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Gene Name: serine threonine kinase 39
Family/Subfamily: Protein Kinase , FRAY
Synonyms: STK39, Serine threonine kinase 39, STE20/SPS1 homolog, Ste20-like protein kinase, DCHT, SPAK, Ste-20-related kinase
Target Sequences: NM_013233 NP_037365.2 Q9UEW8

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
STK39 / SPAK (5)
No (5)
GST, N-terminus (1)
His-S (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
STK39 / SPAK Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
STK39 / SPAK Protein - Recombinant Serine/Threonine Kinase 39 By SDS-PAGE
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E. coli
His-S
61.2 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
STK39 / SPAK Protein - Purified recombinant protein STK39 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
59.3 kDa
20 µg/$1,107
STK39 / SPAK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
59.3 kDa
20 µg/$215
STK39 / SPAK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
59.3 kDa
100 µg/$710
Viewing 1-5 of 5 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).