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STK25
serine/threonine kinase 25
STK25 is a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene.
| Gene Name: | serine/threonine kinase 25 |
| Family/Subfamily: | Protein Kinase , YSK |
| Synonyms: | STK25, SOK-1, Ste20, yeast homolog, Ste20-like kinase, YSK1, Serine/threonine kinase 25, SOK1 |
| Target Sequences: | NM_006374 NP_006365.2 O00506 |
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