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STC1 / Stanniocalcin

stanniocalcin 1

STC1 / Stanniocalcin is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.

Gene Name: stanniocalcin 1
Synonyms: STC1, Stanniocalcin 1, Stanniocalcin, Stanniocalcin-1, STC-1, STC
Target Sequences: NM_003155 NP_003146.1 P52823

Publications (1)

1
Stanniocalcin-1 Protects a Mouse Model from Renal Ischemia-Reperfusion Injury by Affecting ROS-Mediated Multiple Signaling Pathways. Liu D, Shang H, Liu Y. International journal of molecular sciences. 2016 July;17:pii E1051. [Full Text Article] [PubMed:27420048] [PMC:PMC4964427]

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
STC1 / Stanniocalcin (8)
SDS-PAGE (1)
No (8)
6His, C-terminus (1)
DDK (Flag)-His, C-terminus (1)
GST, N-terminus (1)
His, N-Terminal (1)
His,C-terminus (1)
His-GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (7)
293T Cells (1)
E. coli (2)
HEK 293 Cells (3)
Human (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
STC1 / Stanniocalcin Protein
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HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human STC1 consists 241 amino acids and predicts a molecular mass of 27.4 kDa.
100 µg/$480
STC1 / Stanniocalcin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
STC1 / Stanniocalcin Protein - Recombinant Stanniocalcin 1 By SDS-PAGE
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E. coli
His-GST, N-terminus
51.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
STC1 / Stanniocalcin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
27.62 kDa
100 µg/$494
STC1 / Stanniocalcin Protein
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E. coli
His, N-Terminal
27.6 kDa
50 µg/$419
STC1 / Stanniocalcin Protein - Recombinant Human Stanniocalcin 1/STC-1 (C-6His)
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Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
26.9 kDa
10 µg/$334; 50 µg/$608
STC1 / Stanniocalcin Protein
Select
HEK 293 Cells
DDK (Flag)-His, C-terminus
26 kDa
20 µg/$1,107
STC1 / Stanniocalcin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
27.62 kDa
20 µg/$150
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).