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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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STC1 / Stanniocalcin
stanniocalcin 1
STC1 / Stanniocalcin is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
| Gene Name: | stanniocalcin 1 |
| Synonyms: | STC1, Stanniocalcin 1, Stanniocalcin, Stanniocalcin-1, STC-1, STC |
| Target Sequences: | NM_003155 NP_003146.1 P52823 |
Publications (1)
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