STAT6

signal transducer and activator of transcription 6, interleukin-4 induced

STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

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Products

Proteins (11)

Type

Over-Expression Lysate (2)

Recombinant (9)

Target

STAT6 (11)

Publications

No (11)

Tag

6His, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His,C-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (3)

Species

Human (8)

Mouse (1)

Rat (1)

Source

293T Cells (1)

Baculovirus (1)

E. coli (5)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (3)

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Mouse STAT6 Protein (Recombinant His, N-Terminal) (aa410-623) - LS-G14225

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

28.4 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human STAT6 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66967

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

94 kDa

Price:

20 µg/$1,107

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Human STAT6 Protein (Recombinant GST, N-terminus) (aa694-801) - LS-G60231

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human STAT6 Protein (Recombinant 6His, C-terminus) (Ser627-Ser837) - LS-G39728

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

23.9kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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Human STAT6 Protein (Recombinant His-T7) (aa262-520) - LS-G14230

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.7 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Rat STAT6 Protein (Recombinant His-T7) (aa557-841) - LS-G14233

Source:

E. coli

Tag:

His-T7

Molecular Weight:

35.1 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Human STAT6 Protein (Recombinant GST) (Full Length) - LS-G30570

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

100.32 kDa

Price:

10 µg/$479; 25 µg/$670

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STAT6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99983

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

94 kDa

Price:

100 µg/$494

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Human STAT6 Protein (Recombinant His,C-terminus) (Ser627-Ser837) - LS-G140535

Source:

E. coli

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

23.9 kDa

Price:

10 µg/$317; 50 µg/$524

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Human STAT6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78826

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

94 kDa

Price:

20 µg/$150

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Human STAT6 Protein (Recombinant His) (Met1-Trp847) - LS-G97924

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

95.5 kDa

Price:

100 µg/$793

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